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Results for "

acylation

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Acyltransferase (1) Apoptosis (1) Biochemical Assay Reagents (9) Drug Intermediate (3) Endogenous Metabolite (3) Fluorescent Dye (1) Nucleoside Antimetabolite/Analog (1) Phospholipase (1) Reference Standards (1) Ser/Thr Protease (1) Thrombin (1)
By Research Areas:	Cancer (4) Cardiovascular Disease (2) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (1)
Click Chemistry:	Azide (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W883690

LacK free acid	Endogenous Metabolite	Others
LacK (free acid) is a lysine derivative used in lactate acylation studies .

HY-W020983

Trifluoromethanesulfonic acid silver Triflic acid silver; Perfluoromethanesulfonic acid silver; Fluorad FC 24 silver	Biochemical Assay Reagents	Others
Trifluoromethanesulfonic acid (Triflic acid) silver, a perfluoroalkanesulfonic acid, is one of the superior catalysts for C- or O-acylation .

HY-W048838

Acetyl-L-lysine 1 Publications Verification	Endogenous Metabolite	Metabolic Disease
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

HY-W012890

Pentanehydrazide Valeric acid hydrazide	Biochemical Assay Reagents	Others
Pentanehydrazide (Valeric acid hydrazide) is a biochemical reagent that can act as an effective alkylating agent in the copper-catalyzed oxidative cyclization of N-arylacrylamides and participate in the tandem acylation reaction .

HY-41340

2-Aminopyrimidine	Biochemical Assay Reagents Drug Intermediate	Others
2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds .

HY-103006

NAI-N3 5 Publications Verification	Biochemical Assay Reagents	Others
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-155938

Cyano-myracrylamide	Acyltransferase	Neurological Disease Inflammation/Immunology Cancer
Cyano-myracrylamide is an inhibitor of zinc finger DHHC domain-containing palmitoyltransferase 20 (zDHHC20) with an IC₅₀ value of 1.35 µM. Cyano-myracrylamide also inhibits the S-Acylation of EGFR and CD36. Cyano-myracrylamide also inhibits S-acylation of Legionella E3 ligase GobX, MyD88, and Ras, which are substrates of zDHHC20, zDHHC9, and zDHHC6, respectively, in HEK293T cells expressing recombinant Legionella GobX, recombinant human MyD88, or endogenous Ras .

HY-18408

5S rRNA modificator FAI	Biochemical Assay Reagents	Others
5S rRNA modificator is a suitable electrophile for 2’-hydroxyl acylation on structured RNA molecules, yielding accurate structural information comparable to that obtained with existing probes; 5S rRNA RNA modification.

HY-121564

Radermachol	Fluorescent Dye	Others
Radermachol is a red pigment that can be synthesized in four steps via a key ytterbium triflate-catalyzed furan cyclization and intramolecular nucleophilic acylation reaction .

HY-W127410

Hexanoic anhydride	Biochemical Assay Reagents	Others
Hexanoic anhydride is used as a reactant for the synthesis of acremomannolipin A. For the green synthesis of acyclovir dipivoxil (acyclovir proagent), for the preparation of hexanoyl-modified chitosan nanoparticles, chitosan-based polymer surfactants by N-acylation of chitosan .

HY-141570

Lyso-PAF C-16	Phospholipase	Others
Lyso-PAF C-16 is a substrate of lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD). Lyso-PAF C-16 selective acetylates with arachidonic acid .

HY-18407

N-Methylisatoic anhydride	Nucleoside Antimetabolite/Analog	Others
N-Methylisatoic anhydride is a heteronucleoside anhydride derivative conjugated with biotin and a disulfide linker for specific 2'-OH acylation of RNA. Biotin-conjugated N-Methylisatoic anhydride can selectively capture RNA from a mixture of biological RNA and DNA .

HY-41340R

2-Aminopyrimidine (Standard)	Biochemical Assay Reagents Reference Standards Drug Intermediate	Others
2-Aminopyrimidine (Standard) is the analytical standard of 2-Aminopyrimidine (HY-41340). This product is intended for research and analytical applications. 2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds.

HY-117798

LY 806303	Thrombin	Cardiovascular Disease
LY 806303 is a potent and selective inhibitor of human α-thrombin. LY 806303 specifically acylates Ser-205 within the catalytic triad of α-thrombin on the heavy chain and a key site involved in the enzymatic activity of thrombin. The mechanism of action of LY 806303 as an enzyme inhibitor is through the specific acylation of this catalytic serine residue .

HY-125400

Zaragozic acid C L-697350	Endogenous Metabolite	Cancer
Zaragozic acid C (L-697350) is a potent sterol synthase inhibitor with potential antitumor activity. Zaragozic acid C contains multiple hydroxyl and alkyl substituents in its chemical structure, demonstrating complex functionalization capabilities. The synthesis of zaragozic acid C involves a photochemical C(sp3)-H acylation reaction, which resolves the challenging carbon substitution problem in the synthesis .

HY-149552

Ac4-5SGlcNAc	Biochemical Assay Reagents	Cancer
Ac4-5SGlcNAc is a pro-inhibitor of carbohydrate-based glycosyltransferases (OGTs). Ac4-5SGlcNAc inhibits o-GlcN acylation and interferes with the effects of o-GlcN on neural induction of human embryonic stem cells (hESCs), and reduces the invasive phenotype of breast cancer cells. Ac4-5SGlcNAc also targets other carbohydrate-processing enzymes .

HY-126034

3,4-Dichloroisocoumarin	Ser/Thr Protease Apoptosis	Cardiovascular Disease Metabolic Disease Cancer
3,4-Dichloroisocoumarin is a potent serine-protease and SrLip inhibitor (K_i for SrLip: 26.6 μM). 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms .

HY-164899

2A3	Biochemical Assay Reagents	Others
2A3 is a highly efficient and precise SHAPE reagent with powerful biomembrane penetration capabilities, suitable for both in vivo and in vitro RNA structure detection. 2A3 can not only effectively probe most RNA loops but also better capture local nucleotide dynamics, thus enabling it to readily detect regions of ribonucleoprotein complexes that are typically inaccessible to other compounds .

HY-116284

Methyl β-D-glucopyranoside Methyl β-D-glucoside	Drug Intermediate	Others
Methyl β-D-glucopyranoside (Methyl β-D-glucoside) is a model glycosyl acceptor for enzymatic glycosylation reactions. Methyl β-D-glucopyranoside participates in glycoside synthesis and can react with acyl donors such as caffeic acid esters under the catalysis of specific enzymes (such as Lipozyme TL IM) to achieve acylation modification. Methyl β-D-glucopyranoside can generate biologically active derivatives (such as 6-O-caffeoyl glucoside). Methyl β-D-glucopyranoside can be used in organic synthesis and biocatalysis research, especially the efficient enzymatic preparation of medicinal glycosides (such as Robustaside B (HY-N2720), 6-O-caffeoyl salidroside) .

Cat. No.	Product Name	Type

HY-W020983

Trifluoromethanesulfonic acid silver Triflic acid silver; Perfluoromethanesulfonic acid silver; Fluorad FC 24 silver	Biochemical Assay Reagents
Trifluoromethanesulfonic acid (Triflic acid) silver, a perfluoroalkanesulfonic acid, is one of the superior catalysts for C- or O-acylation .

HY-41340

2-Aminopyrimidine	Biochemical Assay Reagents
2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds .

HY-W127410

Hexanoic anhydride	Biochemical Assay Reagents
Hexanoic anhydride is used as a reactant for the synthesis of acremomannolipin A. For the green synthesis of acyclovir dipivoxil (acyclovir proagent), for the preparation of hexanoyl-modified chitosan nanoparticles, chitosan-based polymer surfactants by N-acylation of chitosan .

HY-41340R

2-Aminopyrimidine (Standard)	Biochemical Assay Reagents
2-Aminopyrimidine (Standard) is the analytical standard of 2-Aminopyrimidine (HY-41340). This product is intended for research and analytical applications. 2-Aminopyrimidine is an important heterocyclic intermediate. 2-Aminopyrimidine can undergo various reactions such as alkylation and acylation, and can be used for the synthesis of other active compounds.

Acetyl-L-lysine 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Source classification Metabolic Disease Endogenous metabolite Disease Research Fields	Endogenous Metabolite
Acetyl-L-lysine is an acetylated form of the amino acid L-lysine. Acetyl-L-lysine can participate in protein acylation processes, affecting protein functions such as stability and enzyme activity .

Lyso-PAF C-16	Microorganisms Source classification	Phospholipase
Lyso-PAF C-16 is a substrate of lysoplasmalogen (LysoPls)-specific phospholipase D (LysoPLD). Lyso-PAF C-16 selective acetylates with arachidonic acid .

3,4-Dichloroisocoumarin	Structural Classification Animals Source classification Coumarins Phenylpropanoids	Ser/Thr Protease Apoptosis
3,4-Dichloroisocoumarin is a potent serine-protease and SrLip inhibitor (K_i for SrLip: 26.6 μM). 3,4-Dichloroisocoumarin is opened by serine proteases and then undergoes acylation with the enzyme, thereby inhibiting protease activity. 3,4-Dichloroisocoumarin can induce DNA fragmentation and Apoptosis. 3,4-Dichloroisocoumarin can be used in the research of multiple fields such as tumors, cardiovascular disease and enzyme catalytic mechanisms .

Radermachol	Structural Classification Natural Products Source classification Radermachera xylocarpa (Roxb.) Roxb. ex K.Schum. Bignoniaceae Plants	Fluorescent Dye
Radermachol is a red pigment that can be synthesized in four steps via a key ytterbium triflate-catalyzed furan cyclization and intramolecular nucleophilic acylation reaction .

Zaragozic acid C L-697350	Structural Classification Natural Products Microorganisms Source classification	Endogenous Metabolite
Zaragozic acid C (L-697350) is a potent sterol synthase inhibitor with potential antitumor activity. Zaragozic acid C contains multiple hydroxyl and alkyl substituents in its chemical structure, demonstrating complex functionalization capabilities. The synthesis of zaragozic acid C involves a photochemical C(sp3)-H acylation reaction, which resolves the challenging carbon substitution problem in the synthesis .

Cat. No.	Product Name		Classification

HY-103006

NAI-N3 5 Publications Verification		Azide
NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment) . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

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acylation

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Click Chemistry

Natural
Products