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YTHDF2-IN-1

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173008
    YTHDF2-IN-1

    		Apoptosis YTHDF Cancer
    YTHDF2-IN-1 (Compound CK-75) is the inhibitor for YT521-B homology domain family 2 YTHDF2 (Kd=26.2 μM), that blocks the interaction between YTHDF2 and m6A RNA. YTHDF2-IN-1 inhibits the colony formation of JAR cells, exhibits antiproliferative activity in a variety of cancer cells (IC50 in micromolar levels), arrests the cell cycle at G0/G1 phase, induces apoptosis in K562 .
    YTHDF2-IN-1
  • HY-174982
    YTHDF2 ligand-1

    		YTHDF Cancer
    YTHDF2 ligand-1 (Compound 23) is a selective and high-affinity YTHDF2 ligand with a Kd of 1.3 μM (FP assay) and an IC50 of 11 μM (HTRF assay) . YTHDF2 ligand-1 can be used in the study of cancer .
    YTHDF2 ligand-1

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