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Results for "

U373-MG

" in MedChemExpress (MCE) Product Catalog:

2

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101191
    Ecteinascidin 770
    2 Publications Verification

    Ecteinascidine 770; Et-770

    		 Apoptosis Cancer
    Ecteinascidin 770 (ET-770) is a 1,2,3,4-tetrahydroisoquinoline alkaloid with potent anti-cancer activities; inhibits U373MG cells with an IC50 of 4.83 nM.
    Ecteinascidin 770
  • HY-100155
    4-IBP

    		Sigma Receptor Apoptosis Autophagy Cancer
    4-IBP is a selective σ₁ receptor agonist with high affinity for the σ₁ receptor (Ki =1.7 nM) and moderate affinity for the σ₂ receptor (Ki = 25.2 nM). 4-IBP can make cancer cells more sensitive to the cytotoxic effects of pro-apoptotic and pro-autophagic compounds. 4-IBP significantly reduces the migration ability of a variety of cancer cells. 4-IBP is mainly used in glioblastoma, non-small cell lung cancer and prostate cancer research .
    4-IBP

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