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Results for "

Thiadiazole

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

2

Biochemical Assay Reagents

2

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W032388
    1,3,4-Thiadiazole-2,5-dithiol

    		Biochemical Assay Reagents Others
    1,3,4-Thiadiazole-2,5-dithiol is a reagent for the determination of bismuth, copper and lead .
    1,3,4-Thiadiazole-2,5-dithiol
  • HY-W012675
    2-Amino-5-mercapto-1,3,4-thiadiazole

    		Biochemical Assay Reagents Others
    2-Amino-5-mercapto-1,3,4-thiadiazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    2-Amino-5-mercapto-1,3,4-thiadiazole
  • HY-W006187
    2-Amino-2-(p-tolyl)acetic acid

    		Glutaminase Cancer
    2-Amino-2-(p-tolyl)acetic acid is used for optimizing azide skeleton, and is the intermediate in the synthesis of 1,3, 4-thiadiazole compounds. 1,3,4-thiadiazole compounds exhibit potential anti-cancer activity, and inhibit glutaminase (GLSI) .
    2-Amino-2-(p-tolyl)acetic acid
  • HY-W074975
    CL 5343

    5-Amino-1,3,4-Thiadiazole-2-sulfonamide

    		 Carbonic Anhydrase Cancer
    CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is a selective inhibitor of carbonic anhydrase B (HCA-B) and isoforms I, II, IV, and VII. CL 5343 has a Ki of 7.9 nM for hCA II. CL 5343 acts as a CA9 ligand to achieve targeted delivery of maytansine to the cell membrane of SKRC52 ??renal cancer cells. CL 5343 is useful in the development of therapeutics for diseases associated with CA overactivity, such as glaucoma, epilepsy, and cancer .
    CL 5343
  • HY-108896
    Icatibant acetate
    10+ Cited Publications

    HOE 140 acetate

    		 Bradykinin Receptor Inflammation/Immunology
    Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively .
    Icatibant acetate
  • HY-119403
    4-Phenyl-1,2,3-thiadiazole

    		Cytochrome P450 Cancer
    4-Phenyl-1,2,3-thiadiazole is an CYP2B4 and CYP2E1 inhibitor. 4-Phenyl-1,2,3-thiadiazole inhibits the oxidation of 1-phenylethanol to acetophenone by CYP2B4 and CYP2E1 .
    4-Phenyl-1,2,3-thiadiazole
  • HY-W074975R
    CL 5343 (Standard)

    5-Amino-1,3,4-Thiadiazole-2-sulfonamide (Standard)

    		 Carbonic Anhydrase Reference Standards Cancer
    CL 5343 (Standard) is the analytical standard of CL 5343. This product is intended for research and analytical applications. CL 5343 (5-Amino-1,3,4-thiadiazole-2-sulfonamide) is an inhibitor of human carbonic anhydrase B (HCA-B). CL 5343 can serve as a CA9 ligand to achieve the targeted delivery of maytansinoid to the cell membrane of SKRC52 renal cancer cells .
    CL 5343 (Standard)
  • HY-114955
    MTTC

    		Cytochrome P450 Others
    MTTC is a 1,2,3-thiadiazole compound that exhibits mechanism-based inactivation, resulting in the inactivation of cytochrome P450 2E1 activity .
    MTTC
  • HY-163634
    YZK-C22

    		Fungal Infection
    YZK-C22, containing a 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole skeleton, is a fungicide lead compound with broad-spectrum fungicidal activity .
    YZK-C22
  • HY-106817
    Amitivir

    LY 217896

    		 Influenza Virus Infection
    Amitivir (LY 217896), a thiadiazole derivative, possesses broad antiviral activity against orthomyxo- and paramyxoviruses. Amitivir is effective against influenza A and B viruses .
    Amitivir
  • HY-133073
    CCR7 Ligand 1

    CCR7-Cmp2105

    		 CCR Ligands for Target Protein for PROTAC Cancer
    CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM .
    CCR7 Ligand 1
  • HY-107597
    Halicin
    1 Publications Verification

    SU3327

    		 JNK Metabolic Disease Inflammation/Immunology
    Halicin (SU3327) is a potent, selective and substrate-competitive JNK inhibitor with an IC50 of 0.7 μM. Halicin also inhibits protein-protein interactions between JNK and JNK Interacting Protein (JIP) with an IC50 of 239 nM. Halicin shows less active against p38α and Akt kinase .
    Halicin
  • HY-155240
    Tyrosinase-IN-13

    		Tyrosinase Cancer
    Tyrosinase-IN-13 (compound 3c), a derivative of Flurbiprofen (HY-10582), is a potent, non-competitive tyrosinase inhibitor (IC50=68 μM; Ki=36.3 μM). Tyrosinase-IN-13 is cytotoxic against hepatocellular carcinoma (HepG2), colorectal cancer (HT-29), and melanoma (B16F10) .
    Tyrosinase-IN-13
  • HY-119480R
    Megazol (Standard)

    		Bacterial Infection
    Megazol (Standard) is the analytical standard of Megazol. This product is intended for research and analytical applications. Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
    Megazol (Standard)
  • HY-119480
    Megazol

    		Bacterial Infection
    Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections .
    Megazol

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