Sterilization

By Targets:	Apoptosis (3) Autophagy (3) Bacterial (6) Biochemical Assay Reagents (6) FAK (2) Fungal (1) HIV (2) MMP (2) mTOR (1)
By Research Areas:	Cancer (3) Infection (8) Inflammation/Immunology (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-105840

Dichloramine-T p-Toluenesulfondichloramide	Bacterial	Infection
Dichloramine-T is a strong oxidizer and disinfectant, with strong oxidation and sterilization. Dichloramine-T is also widely used in the medical and health field for disinfection and sterilization operations .

HY-156262

DEPC-Treated Water	Biochemical Assay Reagents	Others
DEPC-Treated Water is ultrapure water that has been sterilized by high temperature and high pressure and does not contain nuclease. It can avoid contamination by non-specific endonucleases and exonucleases and does not affect RNase activity .

HY-W010520

Methylisothiazolinone	Bacterial MMP Apoptosis Fungal	Infection Inflammation/Immunology
Methylothiazolinone is a bacterial and fungal inhibitor and preservative, as well as a sensitizer. Methylisothiazolinone can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce apoptosis and inflammatory response. Methylisothiazolinone can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone can cause mitochondrial damage in the endothelium of rat cerebral blood vessels .

HY-Y0320D

Dimethyl sulfoxide, cryoprotectant vitrification agent DMSO, cryoprotectant vitrification agent; Dimethyl sulfoxide vitrification agent	Biochemical Assay Reagents	Others
Dimethyl sulfoxide, cryoprotectant vitrification agent (DMSO, cryoprotectant vitrification agent) is a biochemical reagent that can be used as a biological material or organic compound for life science related research . This product has been sterilized and has no endotoxin. It can be used for long-term cell cryopreservation and will not affect the normal growth of cells.

HY-W010520R

Methylisothiazolinone (Standard)	Bacterial MMP	Infection Inflammation/Immunology
Methylisothiazolinone (Standard) is the analytical standard of Methylisothiazolinone. Methylothiazolinone is a fungicide and preservative, as well as a sensitizer. Methylisothiazolinone can activate matrix metalloproteinases (MMPs) in human bronchial epithelial cells to induce cell apoptosis and inflammatory response. Methylisothiazolinone can promote the development of atopic dermatitis in mice by disrupting Th2/Th17 related immune responses. Methylisothiazolinone can cause mitochondrial damage in the endothelium of rat cerebral blood vessels .

HY-150137

Iomeprol	Biochemical Assay Reagents	Others
Iomeprol is a nonionic X-ray contrast agent with low osmotic pressure, stable chemical properties, and can withstand high temperature sterilization. Iomeprol can be widely used in vascular, body cavity, and gastrointestinal angiography examinations .

HY-E70005P

Collagenase (Type B, filtered, animal free)	Biochemical Assay Reagents	Others
Collagenase (Type B, animal free) does not contain animal-related components, and is sterilized by filtration using a 0.22 μm filter membrane. Collagenase (Type B, filtered, animal free) has higher collagenase and casein activity.

HY-E70005O

Collagenase (Type A, filtered, animal free)	Biochemical Assay Reagents	Others
Collagenase (Type A, filtered, animal free) does not contain animal-related components, and is sterilized by filtration using a 0.22 μm filter membrane. Collagenase (Type A, filtered, animal free) has collagenase activity similar to type 1 and type 2 collagenase.

HY-E70005Q

Collagenase (Type C, filtered, animal free)	Biochemical Assay Reagents	Others
Collagenase (Type C, filtered, animal free) does not contain animal-related components, and is sterilized by filtration using a 0.22 μm filter membrane. Collagenase (Type C, filtered, animal free) has low trypsin activity similar to type 4 collagenase.

HY-P10526

CRAMP (1-39)	Bacterial	Infection
CRAMP (1-39) is an antimicrobial peptide. CRAMP (1-39) has shown potent bactericidal effects against multiple strains of Neisseria meningitidis in vitro. CRAMP (1-39) can be used to study drug-resistant bacterial infections .

HY-162142

BB2-50F	Bacterial	Infection
BB2-50F is a potent and multi-targeting bioenergetic bactericidal inhibitor of *M. tuberculosis* and can sterilizes replicating and non-replicating *M. tuberculosis. BB2-50F inhibits succinate oxidation, decreases the activity of the tricarboxylic acid (TCA) cycle, and results in succinate secretion from M. tuberculosis*.

HY-N1372A

Fangchinoline 5+ Cited Publications	HIV FAK Apoptosis Autophagy	Infection Cancer
Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing . Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK . Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer .

HY-N1372AR

Fangchinoline (Standard)	HIV FAK Apoptosis Autophagy	Infection Cancer
Fangchinoline (Standard) is the analytical standard of Fangchinoline. This product is intended for research and analytical applications. Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing . Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK . Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer .

HY-145931

CC214-2	mTOR Autophagy	Cancer
CC214-2 is an oral active and selective mTOR kinase inhibitor. CC214-2 targets to both of mTORC1 (pS6) and mTORC2 (pAktS473). CC214-2 induces autophagy, which is a potential target for host-directed therapy (HDT) in tuberculosis. CC214-2 exhibits synergistic bactericidal and sterilizing activity agasinst tuberculosis (TB), and shortens the treatment duration. CC214-2 also inhibits Rapamycin (HY-10219)-resistant signaling and the growth of glioblastomas in vitro and in vivo .

HY-161988

Antimicrobial agent-34	Bacterial	Infection Inflammation/Immunology
Antimicrobial agent-34 (compound 4h) is an antibacterial agent (MIC = 1–4 μg/mL), with a clogP value of 9.14. Antimicrobial agent-34 has good plasma stability (HC₅₀ of 131.1 μg/mL) and good membrane selectivity (HC₅₀/MIC is 65.6), with rapid sterilization capability. Antimicrobial agent-34 destroys the integrity of bacterial cell membranes, induces an increase in intracellular reactive oxygen species, and leaks protein and DNA, ultimately leading to bacterial death. Antimicrobial agent-34 demonstrates significant in vivo antibacterial potency in a mouse sepsis model infected with Staphylococcus aureus ATCC43300 .

Cat. No.	Product Name	Type

HY-156262

DEPC-Treated Water	Gene Sequencing and Synthesis
DEPC-Treated Water is ultrapure water that has been sterilized by high temperature and high pressure and does not contain nuclease. It can avoid contamination by non-specific endonucleases and exonucleases and does not affect RNase activity .

HY-Y0320D

Dimethyl sulfoxide, cryoprotectant vitrification agent DMSO, cryoprotectant vitrification agent; Dimethyl sulfoxide vitrification agent	Co-solvents
Dimethyl sulfoxide, cryoprotectant vitrification agent (DMSO, cryoprotectant vitrification agent) is a biochemical reagent that can be used as a biological material or organic compound for life science related research . This product has been sterilized and has no endotoxin. It can be used for long-term cell cryopreservation and will not affect the normal growth of cells.

Cat. No.	Product Name	Target	Research Area

HY-P10526

CRAMP (1-39)	Bacterial	Infection
CRAMP (1-39) is an antimicrobial peptide. CRAMP (1-39) has shown potent bactericidal effects against multiple strains of Neisseria meningitidis in vitro. CRAMP (1-39) can be used to study drug-resistant bacterial infections .

Cat. No.	Product Name

HY-K3009

0.25% Trypsin-EDTA (1×), no phenol red
MCE 0.25% Trypsin-EDTA (1×), Phenol Red-Free, is prepared by dissolving trypsin powder (a mixture of proteases from porcine pancreas, irradiated and sterilized) and EDTA in a calcium- and magnesium-free balanced salt solution. It is filter-sterilized and can be directly used for the dissociation of cultured cells and tissues.

HY-E0224

0.5 mL Storage Tube
0.5 mL Storage Tube, Three-Code Tube, External Thread with Screw Cap, Compatible with SBS- 96-Well Racks. This product is made from high-quality PP material, suitable for ultra-low temperature storage, with excellent weather resistance. Free from DNase and RNase, and can be sterilized by irradiation. The bottom of the tube features a unique QR code, while the side wall has a 1D linear barcode and directly readable numeric code, all three codes are identical and unique. The codes are laser-etched, scratch-resistant, not easy to fall off, and have high contrast for easy reading. The accompanying tube rack (HY-E0225) is made of the same material as the tube, effectively preventing uneven expansion issues during freeze-thaw cycles.

0.5 mL Storage Tube

0.5 mL Storage Tube, Three-Code Tube, External Thread with Screw Cap, Compatible with SBS- 96-Well Racks. This product is made from high-quality PP material, suitable for ultra-low temperature storage, with excellent weather resistance. Free from DNase and RNase, and can be sterilized by irradiation. The bottom of the tube features a unique QR code, while the side wall has a 1D linear barcode and directly readable numeric code, all three codes are identical and unique. The codes are laser-etched, scratch-resistant, not easy to fall off, and have high contrast for easy reading. The accompanying tube rack (HY-E0225) is made of the same material as the tube, effectively preventing uneven expansion issues during freeze-thaw cycles.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1372A

Fangchinoline 5+ Cited Publications	Stephania tetrandra S. Moore Infection Alkaloids Structural Classification Monophenols Classification of Application Fields Source classification Phenols Plants Isoquinoline Alkaloids Menispermaceae Disease Research Fields	HIV FAK Apoptosis Autophagy
Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing . Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK . Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer .

HY-N1372AR

Fangchinoline (Standard)	Stephania tetrandra S. Moore Alkaloids Structural Classification Monophenols Source classification Phenols Plants Isoquinoline Alkaloids Menispermaceae	HIV FAK Apoptosis Autophagy
Fangchinoline (Standard) is the analytical standard of Fangchinoline. This product is intended for research and analytical applications. Fangchinoline is isolated from Stephania tetrandra with extensive biological activities, such as enhancing immunity, anti-inflammatory sterilization and anti-atherosclerosis. Fangchinoline, a novel HIV-1 inhibitor, inhibits HIV-1 replication by impairing gp160 proteolytic processing . Fangchinoline targets Focal adhesion kinase (FAK) and suppresses FAK-mediated signaling pathway in tumor cells which highly expressed FAK . Fangchinoline induces apoptosis and adaptive autophagy in bladder cancer .

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