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Results for "

SPM

" in MedChemExpress (MCE) Product Catalog:

12

Inhibitors & Agonists

2

Natural
Products

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-112402
    SP 600125, negative control

    JNK Inhibitor II, negative control

    		 Autophagy Apoptosis JNK Ferroptosis Cancer
    SP 600125，negative control (SPM1) is an alkyl derivative of pyrazoloanthrone，which can be used as a negative control for SP600125 (HY-12041) .
    SP 600125, negative control
  • HY-113512
    17-HDHA

    		Influenza Virus Inflammation/Immunology
    17-HDHA is a DHA-derived specialized proresolving mediator (SPM). 17-HDHA enhances the antibody-mediated immune response against influenza virus. 17-HDHA enhances the differentiation of B cells toward the CD27 + CD38 + antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells .
    17-HDHA
  • HY-126837
    SPM VIII

    Spicamycin VIII

    		 Antibiotic Cancer
    SPM VIII is a dodecanoyl analogue of spicamycin, a nucleoside antibiotic that contains fatty acids of various chain lengths. SPM VIII exhibits potent antitumor activity against the human gastric cancer SC-9 xenograft model .
    SPM VIII
  • HY-163044
    C12-SPM

    		Liposome Infection
    C12-SPM is a lipid that mediates siRNA delivery. C12-SPM has no significant cytotoxicity and can be used for research on hepatoviral diseases .
    C12-SPM
  • HY-160569
    C14-SPM

    		Liposome Inflammation/Immunology
    C14-SPM is a polyamine branched-chain lipidoid that can be used for the delivery of siRNA .
    C14-SPM
  • HY-120255A
    17(S)-HDHA

    		PPAR Metabolic Disease
    17(S)-HDHA is a pro-resolving mediator (SPM). 17(S)-HDHA slightly activats PPARγ, PPARα and PPARδ .
    17(S)-HDHA
  • HY-130322
    Maresin Conjugates in Tissue Regeneration 2

    MCTR2

    		 Others Inflammation/Immunology
    Maresin Conjugates in Tissue Regeneration 2 is a specialized pro-resolving mediator (SPM). Maresin Conjugates in Tissue Regeneration 2 can be used in the study of anti-inflammatory .
    Maresin Conjugates in Tissue Regeneration 2
  • HY-125445
    PCTR1

    		Bacterial Inflammation/Immunology
    PCTR1 is a potent monocyte/macrophage agonist, regulating key anti-inflammatory and pro-resolving processes during bacterial infection. PCTR1 is a member of the protectin family of specialized pro-resolving mediators (SPMs) .
    PCTR1
  • HY-120255
    17(R)-HDHA

    17(R)-HDoHE

    		 Drug Derivative Inflammation/Immunology
    17(R)-HDHA (17(R)-HDoHE) is a pro-resolving mediator (SPM). 17(R)-HDHA enhances the differentiation of B cells toward the CD27(+)CD38(+) antibody-secreting cell phenotype, thereby strongly increasing IgM and IgG production by activated B cells. 17(R)-HDHA does not affect cell proliferation and is non-toxic to cells .
    17(R)-HDHA
  • HY-145491
    Resolvin D5

    		ERK NF-κB Inflammation/Immunology
    Resolvin D5 is a prolytic mediator (SPM) with anti-inflammatory activity derived from oxidized lipids DHA. Resolvin D5 inhibits Th17 cell differentiation and promotes regulatory T cell differentiation, and inhibits CD4+ T cell proliferation. Resolvin D5 attenuates osteoclast differentiation and interferes with osteoclastogenesis. Resolvin D5 also regulates ERK phosphorylation and nuclear translocation of NF-kappaB. Resolvin D5 could be used in rheumatoid arthritis research .
    Resolvin D5
  • HY-168782
    Resolvin D2 n-3 DPA

    		TNF Receptor Interleukin Related Inflammation/Immunology
    Resolvin D2 n-3 DPA is a specialized proresolving mediator (SPM). Resolvin D2 n-3 DPA (1 nM) can reduce the chemotaxis and adhesion of human neutrophils induced by TNF-α. Resolvin D2 n-3 DPA (100 ng/mouse; intravenous injection) can reduce neutrophil infiltration in the peritoneum and the levels of IL-6 and the chemokine (C-C motif) ligand 2 (CCL2) in a mouse model of inflammation induced by zinc oxide .
    Resolvin D2 n-3 DPA
  • HY-113509B
    15(R)-Lipoxin A4

    15-epi-LXA4

    		 STAT Neurological Disease Inflammation/Immunology
    15(R)-Lipoxin A4 (15-epi-LXA4) is a STAT-6 activator and a lipid-derived lipoxin-type specialized pro-resolving mediator (SPM) that plays a role in promoting inflammation resolution and regulating immune cell function. 15(R)-Lipoxin A4 can improve the phagocytic function of microglia and exhibits anti-inflammatory activity. In Alzheimer's disease (AD) mouse models, 15(R)-Lipoxin A4 improves AD-like pathology. 15(R)-Lipoxin A4 holds potential for use in inflammation and neurodegenerative disease research .
    15(R)-Lipoxin A4

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