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Results for "

SP 11

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-172942
    SP11

    		Reactive Oxygen Species (ROS) Cardiovascular Disease Neurological Disease Cancer
    SP11 is a mitochondrial reactive oxygen species (ROS) inhibitor. SP11 activates Fis1 by binding to Cys41 (IC50: 9.4 µM) and increases the translocation of Drp1 to mitochondria. SP11 can be used in studies on the protection against oxidative stress damage .
    SP11
  • HY-100008R
    Peretinoin (Standard)

    NIK333 (Standard)

    		 Reference Standards RAR/RXR SphK Autophagy HCV Infection Cancer
    Peretinoin (Standard) is the analytical standard of Peretinoin. This product is intended for research and analytical applications. Peretinoin is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as retinoid X receptor (RXR) and retinoic acid receptor (RAR). Peretinoin reduces the mRNA level of sphingosine kinase 1 (SPHK1) in vitro by downregulating a transcription factor, Sp1[1]. Peretinoin prevents the progression of non-alcoholic steatohepatitis (NASH) and the development of hepatocellular carcinoma (HCC) through activating the autophagy pathway by increased Atg16L1 expression[2]. Peretinoin inhibits HCV RNA amplification and virus release by altering lipid metabolism with a EC50 of 9 μM[3].
    Peretinoin (Standard)
  • HY-RS16562
    Sp1 Mouse Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    Sp1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Sp1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Sp1 Mouse Pre-designed siRNA Set A
    Sp1 Mouse Pre-designed siRNA Set A

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