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Ribocil

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-19487

    Bacterial Infection
    Ribocil is a selective inhibitor targeting the bacterial FMN riboswitch, regulating the bacterial riboflavin riboswitch. Ribocil competitively binds to the FMN binding site, mimicking the natural ligand FMN to induce conformational changes in the riboswitch, inhibiting ribB gene expression, reducing riboflavin synthesis, and thus inhibiting bacterial growth. Ribocil strongly inhibits GFP expression (EC50=0.3 μM). Ribocil exhibits in vivo antibacterial activity in a mouse model and can be used to study antibacterial drugs related to drug-resistant bacterial infections and bacterial riboflavin metabolic pathways[1][2].
    Ribocil
  • HY-19488

    Bacterial Infection
    Ribocil-C Racemate is the racemate of Ribocil-C. Ribocil-C is a highly selective inhibitor of bacterial riboflavin riboswitches.
    Ribocil-C Racemate
  • HY-19488B

    Bacterial Infection
    Ribocil-C R enantiomer is the R enantiomer of Ribocil-C. Ribocil-C is a highly selective inhibitor of bacterial riboflavin riboswitches.
    Ribocil-C (R enantiomer)
  • HY-19488A
    Ribocil-C
    1 Publications Verification

    Bacterial Infection
    Ribocil-C is a highly selective inhibitor of bacterial riboflavin riboswitches.
    Ribocil-C
  • HY-19487A

    Ribocil S enantiomer; ent-Ribocil A

    Bacterial Infection
    Ribocil-B is the active S-isomer of ribocil which can inhibit flavin mononucleotide (FMN) with a KD of 6.6 nM.
    Ribocil B

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