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PS-10

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2

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-121744
    PS10
    3 Publications Verification

    PDHK Inflammation/Immunology
    PS10 is a novel, potent and ATP-competitive pan-PDK inhibitor, inhibits all PDK isoforms with IC50 of 0.8 μM, 0.76 μM, 2.1 μM and 21.3 μM for PDK2, PDK4, PDK1, and PDK3, respectively. PS10 shows high affinity for PDK2 (Kd= 239 nM) than for Hsp90 (Kd= 47 μM) . PS10 improves glucose tolerance, stimulates myocardial carbohydrate oxidation in diet-induced obesity. PS10 has the potential for the investigation of diabetic cardiomyopathy .PDK: pyruvate dehydrogenase kinase
    PS10
  • HY-RS28365

    Small Interfering RNA (siRNA) Others
    Eef1a2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Eef1a2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Eef1a2 Rat Pre-designed siRNA Set A
    Eef1a2 Rat Pre-designed siRNA Set A

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