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Results for "

PHFs

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (3) Autophagy (2) Biochemical Assay Reagents (1) Histone Demethylase (3) Reference Standards (1) Small Interfering RNA (siRNA) (32) Tau Protein (5)
By Research Areas:	Cancer (3) Neurological Disease (8)
Oligonucleotides:	Rat Pre-designed siRNA Sets (6) Mouse Pre-designed siRNA Sets (7) Human Pre-designed siRNA Sets (19) siRNAs (32)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Natural
Products

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P4822

*Acetyl-PHF5 amide*	Tau Protein	Others
Acetyl-PHF5 amide is an amyloidogenic protein tau peptide. Acetyl-PHF5 amide can polymerization into filamentous structures .

HY-RS29236

Phf12 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf12 Rat Pre-designed siRNA Set A contains three designed siRNAs for Phf12 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf12 Rat Pre-designed siRNA Set A Phf12 Rat Pre-designed siRNA Set A

HY-RS10421

PHF20 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF20 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF20 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF20 Human Pre-designed siRNA Set A PHF20 Human Pre-designed siRNA Set A

HY-RS24516

Phf8 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf8 Rat Pre-designed siRNA Set A contains three designed siRNAs for Phf8 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf8 Rat Pre-designed siRNA Set A Phf8 Rat Pre-designed siRNA Set A

HY-RS29238

Phf23 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf23 Rat Pre-designed siRNA Set A contains three designed siRNAs for Phf23 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf23 Rat Pre-designed siRNA Set A Phf23 Rat Pre-designed siRNA Set A

HY-RS22725

Phf24 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf24 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phf24 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf24 Mouse Pre-designed siRNA Set A Phf24 Mouse Pre-designed siRNA Set A

HY-RS25856

Phf6 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf6 Rat Pre-designed siRNA Set A contains three designed siRNAs for Phf6 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf6 Rat Pre-designed siRNA Set A Phf6 Rat Pre-designed siRNA Set A

HY-RS10429

PHF6 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF6 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF6 Human Pre-designed siRNA Set A PHF6 Human Pre-designed siRNA Set A

HY-RS10425

PHF23 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF23 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF23 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF23 Human Pre-designed siRNA Set A PHF23 Human Pre-designed siRNA Set A

HY-RS18042

Phf8 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf8 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phf8 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf8 Mouse Pre-designed siRNA Set A Phf8 Mouse Pre-designed siRNA Set A

HY-RS10415

PHF11 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF11 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF11 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF11 Human Pre-designed siRNA Set A PHF11 Human Pre-designed siRNA Set A

HY-RS29239

Phf24 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf24 Rat Pre-designed siRNA Set A contains three designed siRNAs for Phf24 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf24 Rat Pre-designed siRNA Set A Phf24 Rat Pre-designed siRNA Set A

HY-RS10420

PHF2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF2 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF2 Human Pre-designed siRNA Set A PHF2 Human Pre-designed siRNA Set A

HY-RS29237

Phf19 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf19 Rat Pre-designed siRNA Set A contains three designed siRNAs for Phf19 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf19 Rat Pre-designed siRNA Set A Phf19 Rat Pre-designed siRNA Set A

HY-RS10428

PHF5A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF5A Human Pre-designed siRNA Set A contains three designed siRNAs for PHF5A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF5A Human Pre-designed siRNA Set A PHF5A Human Pre-designed siRNA Set A

HY-RS10417

PHF13 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF13 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF13 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF13 Human Pre-designed siRNA Set A PHF13 Human Pre-designed siRNA Set A

HY-RS19628

Phf2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phf2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf2 Mouse Pre-designed siRNA Set A Phf2 Mouse Pre-designed siRNA Set A

HY-RS10423

PHF21A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF21A Human Pre-designed siRNA Set A contains three designed siRNAs for PHF21A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF21A Human Pre-designed siRNA Set A PHF21A Human Pre-designed siRNA Set A

HY-RS10419

PHF19 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF19 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF19 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF19 Human Pre-designed siRNA Set A PHF19 Human Pre-designed siRNA Set A

HY-RS22723

Phf19 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf19 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phf19 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf19 Mouse Pre-designed siRNA Set A Phf19 Mouse Pre-designed siRNA Set A

HY-RS10418

PHF14 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF14 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF14 Human Pre-designed siRNA Set A PHF14 Human Pre-designed siRNA Set A

HY-RS10426

PHF24 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF24 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF24 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF24 Human Pre-designed siRNA Set A PHF24 Human Pre-designed siRNA Set A

HY-RS10414

PHF10 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF10 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF10 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF10 Human Pre-designed siRNA Set A PHF10 Human Pre-designed siRNA Set A

HY-RS19364

Phf6 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf6 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phf6 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf6 Mouse Pre-designed siRNA Set A Phf6 Mouse Pre-designed siRNA Set A

HY-RS10413

PHF1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF1 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF1 Human Pre-designed siRNA Set A PHF1 Human Pre-designed siRNA Set A

HY-RS10431

PHF8 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF8 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF8 Human Pre-designed siRNA Set A PHF8 Human Pre-designed siRNA Set A

HY-RS10427

PHF3 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF3 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF3 Human Pre-designed siRNA Set A PHF3 Human Pre-designed siRNA Set A

HY-RS22722

Phf12 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf12 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phf12 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf12 Mouse Pre-designed siRNA Set A Phf12 Mouse Pre-designed siRNA Set A

HY-RS22724

Phf23 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Phf23 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Phf23 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Phf23 Mouse Pre-designed siRNA Set A Phf23 Mouse Pre-designed siRNA Set A

HY-RS10416

PHF12 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF12 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF12 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF12 Human Pre-designed siRNA Set A PHF12 Human Pre-designed siRNA Set A

HY-RS10430

PHF7 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF7 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF7 Human Pre-designed siRNA Set A PHF7 Human Pre-designed siRNA Set A

HY-P4808A

PHF6 TFA	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is mapped to the third microtubule-binding repeat region of the tau protein .

HY-RS10424

PHF21B Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF21B Human Pre-designed siRNA Set A contains three designed siRNAs for PHF21B gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF21B Human Pre-designed siRNA Set A PHF21B Human Pre-designed siRNA Set A

HY-RS10422

PHF20L1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
PHF20L1 Human Pre-designed siRNA Set A contains three designed siRNAs for PHF20L1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PHF20L1 Human Pre-designed siRNA Set A PHF20L1 Human Pre-designed siRNA Set A

HY-P2516

Tau Peptide (275-305) (Repeat 2 domain)	Tau Protein	Neurological Disease
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein .

HY-P1675A

*Acetyl-PHF6 amide TFA* 1 Publications Verification AcPHF6 TFA; Ac-VQIVYK-NH2 TFA	Tau Protein	Neurological Disease
Acetyl-PHF6 amide TFA (AcPHF6 TFA) is a tau derived hexapeptide.

HY-P991376

BIIB076	Tau Protein	Neurological Disease
BIIB076 is a human monoclonal antibody (mAb) targeting *PHF-tau*. BIIB076 can be used for passive immunity research in Alzheimer's disease (AD) .

HY-138643

Cl-NQTrp	Amyloid-β	Neurological Disease
Cl-NQTrp signifcantly disrupts the preformed fbrillar aggregates of Tau-derived PHF6 (VQIVYK) peptide and full-length tau protein .

HY-P4808

PHF6	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P991373

APNmAb005	Tau Protein	Neurological Disease
APNmAb005 is a human monoclonal antibody (mAb) targeting *MAPT/Tau/PHF-tau*. APNmAb005 blocks tau seeding in vitro and rescues neuronal loss in rTG4510 mice. APNmAb005 can be used in Alzheimer’s disease (AD) research .

HY-153608

JHDM-IN-1	Histone Demethylase	Cancer
JHDM-IN-1 (Compound 1) is a Jumonji C domain-containing HDMs (JHDM) inhibitor with IC₅₀s of 3.4, 4.3, 5.9, 10 and 43 μM against JMJD2C, JMJD2A, JMJD2E, PHF8 and JMJD3, respectively .

HY-13643

Daminozide 2 Publications Verification	Histone Demethylase	Cancer
Daminozide, a plant growth regulator, is a selective inhibitor of the human KDM2/7 histone demethylases, with IC₅₀s of 0.55, 1.5 and 2.1 μM for *PHF8, KDM2A, and KIAA1718*, respectively. Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested .

HY-13643R

Daminozide (Standard)	Reference Standards Histone Demethylase	Cancer
Daminozide (Standard) is the analytical standard of Daminozide. This product is intended for research and analytical applications. Daminozide, a plant growth regulator, is a selective inhibitor of the human KDM2/7 histone demethylases, with IC50s of 0.55, 1.5 and 2.1 μM for PHF8, KDM2A, and KIAA1718, respectively. Daminozide has >100-fold selectivity for KDM2/7 subfamily versus other demethylase subfamily members tested .

HY-137557

Florzolotau APN1607; PM-PBB3	Biochemical Assay Reagents	Neurological Disease
Florzolotau (APN1607) is a positron emission tomography (PET) ligand that can be used to detect Alzheimer's disease (AD) and other tau proteinopathies. Its binding sites are located in the β-helix of the paired helical filaments (PHFs) and straight filaments (SFs) of the tau protein, as well as in the C-shaped cavity of the SFs. In addition, APN-1607 can bind to the intraneuronal inclusions in Alzheimer's disease (AD), primary age-related tauopathy (PART), and posterior cortical atrophy (PCA). Florzolotau is expected to be used in PET imaging research of neurological diseases, especially tau proteinopathies .

Cat. No.	Product Name	Target	Research Area

HY-P4808A

PHF6 TFA	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) TFA is a self-assembly sequence capable of initiating the full-length tau protein aggregation. PHF6 TFA is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P2516

Tau Peptide (275-305) (Repeat 2 domain)	Tau Protein	Neurological Disease
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein .

HY-P1675A

*Acetyl-PHF6 amide TFA* 1 Publications Verification AcPHF6 TFA; Ac-VQIVYK-NH2 TFA	Tau Protein	Neurological Disease
Acetyl-PHF6 amide TFA (AcPHF6 TFA) is a tau derived hexapeptide.

HY-P4822

*Acetyl-PHF5 amide*	Tau Protein	Others
Acetyl-PHF5 amide is an amyloidogenic protein tau peptide. Acetyl-PHF5 amide can polymerization into filamentous structures .

HY-P4808

PHF6	Amyloid-β Autophagy	Neurological Disease
PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein .

HY-P4819

*Acetyl-PHF4 amide*	Peptides	Others
Acetyl-PHF4 amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4824

*Acetyl-PHF6KE amide*	Peptides	Others
Acetyl-PHF6KE amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4826

*Acetyl-PHF6QV amide*	Peptides	Others
Acetyl-PHF6QV amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

HY-P4828

*Acetyl-PHF6YA amide*	Peptides	Others
Acetyl-PHF6YA amide is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development .

Cat. No.	Product Name	Target	Research Area