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PDHK1-IN-2

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-173298
    PDHK1-IN-2

    		PDHK Inflammation/Immunology Cancer
    PDHK1-IN-2 (Compound 24) is an ATP-competitive dual inhibitor of pyruvate dehydrogenase kinases 1/2 (PDHK1/2), with an IC50 of 0.007 μM for PDHK1 and an IC50 of 0.015 μM for PDHK2. PDHK1-IN-2 can regulate immune cell metabolism and correct mitochondrial dysfunction, and is expected to be used in the research of autoimmune diseases, inflammatory diseases, cancers, and other conditions .
    PDHK1-IN-2

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