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NLRP3-IN-77

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-171589
    NLRP3-IN-77

    		NOD-like Receptor (NLR) Interleukin Related Inflammation/Immunology Cancer
    NLRP3-IN-77 (Compound 7n) is a potent NLRP3 inflammasome inhibitor. NLRP3-IN-77 inhibits the viability of THP-1 cells with an IC50 value of 5.36 nM. NLRP3-IN-77 can effectively reduce the secretion of interleukin-1β (IL-1β) and interleukin-18 (IL-18). NLRP3-IN-77 is promising for research of diseases related to the abnormal activation of the NLRP3 inflammasome, such as cancer and inflammatory diseases .
    NLRP3-IN-77

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