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Results for "

MLT

" in MedChemExpress (MCE) Product Catalog:

13

Inhibitors & Agonists

1

Natural
Products

1

Antibodies

4

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-131902
    MLT-231

    		MALT1 Cancer
    MLT-231 is a potent, highly selective allosteric MALT1 Inhibitor with an IC50 of 9 nM. MLT-231 specifically prevents endogenous BCL10 cleavage with IC50 of 160 nM. MLT-231 shows antitumor activity in an ABC-DLBCL type xenograft model in mouse .
    MLT-231
  • HY-142648
    MLT-985

    		MALT1 Cancer
    MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.
    MLT-985
  • HY-134820
    MLT-943

    		MALT1 Inflammation/Immunology
    MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. MLT-943 inhibits stimulated-IL-2 secretion in PBMC or in whole blood with a similar IC50 across species (0.07-0.09 μM in PBMC, 0.6-0.8 μM in whole blood). MLT-943 has anti-inflammatory activities and can be used for FcgR-mediated inflammation research .
    MLT-943
  • HY-115466
    MLT-748
    4 Publications Verification

    		 MALT1 Inflammation/Immunology
    MLT-748 is a potent, selective and allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 5 nM .
    MLT-748
  • HY-124587
    MLT-747

    		MALT1 Inflammation/Immunology
    MLT-747 is a potent, selective, allosteric inhibitor of MALT1, binds MALT1 in the allosteric Trp580 pocket, with an IC50 of 14 nM .
    MLT-747
  • HY-163028
    ML-T7

    		Tim3 Cancer
    ML-T7 is a potent Tim-3 inhibitor. ML-T7 blocks Tim-3 interactions with PtdSer and CEACAM1. ML-T7 not only enhances the antitumor activity of adoptive transfer therapy with cytotoxic T lymphocytes (CTLs) and CAR T cells but also increases the effector function of T cell. ML-T7 promotes NK cells’ killing activity against tumor cells and DC antigen-presenting capacity. ML-T7 directly exerts antitumor efficacy in preclinical tumor models either alone or in combination with Nivolumab (HY-P9903A). ML-T7 can be used for tumor immunotherapy research .
    ML-T7
  • HY-RS07995
    MALT1 Human Pre-designed siRNA Set A

    MLT; MLT1; IMD12; PCASP1

    		 Small Interfering RNA (siRNA) Others

    MALT1 Human Pre-designed siRNA Set A contains three designed siRNAs for MALT1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MALT1 Human Pre-designed siRNA Set A
    MALT1 Human Pre-designed siRNA Set A
  • HY-RS08055
    MAP3K20 Human Pre-designed siRNA Set A

    pk; AZK; MLT; MRK; ZAK; CNM6; MLK7; MLTK; SFMMP; mlklak; MLTKbeta; MLTKalpha

    		 Small Interfering RNA (siRNA) Others

    MAP3K20 Human Pre-designed siRNA Set A contains three designed siRNAs for MAP3K20 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MAP3K20 Human Pre-designed siRNA Set A
    MAP3K20 Human Pre-designed siRNA Set A
  • HY-RS22575
    Insm2 Mouse Pre-designed siRNA Set A

    MLT1

    		 Small Interfering RNA (siRNA) Others

    Insm2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Insm2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

    Insm2 Mouse Pre-designed siRNA Set A
    Insm2 Mouse Pre-designed siRNA Set A
  • HY-RS06845
    INSM2 Human Pre-designed siRNA Set A

    IA6; IA-6; MLT1

    		 Small Interfering RNA (siRNA) Others

    INSM2 Human Pre-designed siRNA Set A contains three designed siRNAs for INSM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    INSM2 Human Pre-designed siRNA Set A
    INSM2 Human Pre-designed siRNA Set A
  • HY-142648A
    (R)-MLT-985

    		MALT1 Cancer
    (R)-MLT-985 (compound 11) is a potent MALT1 protease inhibitor with an IC50 of 3 nM. (R)-MLT-985 has an IC50 of 20 nM for MALT1-dependent IL-2 production in Jurkat cells. (R)-MLT-985 suppresses growth and aberrant CARD11/BCL10/MALT1 complex signaling in ABC-DLBCL cells .
    (R)-MLT-985
  • HY-N14782
    10-Decarbomethoxyaclacinomycin A

    		Antibiotic Bacterial Infection Cancer
    10-Decarbomethoxyaclacinomycin A is an anthracycline antibiotic can be produced by Streptomyces galilaeus MA144-Mlt mutant strain KE303. 10-Decarbomethoxyaclacinomycin A has antibacterial activities .
    10-Decarbomethoxyaclacinomycin A
  • HY-169382
    Melatonin-Tamoxifen Conjugate

    		Melatonin Receptor Cancer
    Melatonin-Tamoxifen Conjugate (compound 16c) is an anticancer drug conjugate composed of Melatonin (HY-B0075) and Tamoxifen (HY-13757A), which is a potent antagonist of ERα (IC50=863 nM). Melatonin-Tamoxifen Conjugate binds to MLT receptor (Ki=3.1 nM) and promotes β-arrestin (EC50=914 nM) and ERK activation (EC50=98 nM) in cells expressing hMT1 receptor. Melatonin-Tamoxifen Conjugate against several common cell lines MCF-7, MDA-MB-231, and HT-1080 with IC50s of 6.8 μM, 6.4 μM, and 1.7 μM, respectively.
    Melatonin-Tamoxifen Conjugate

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