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Results for "

MICS 1

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (3) Bacterial (9) Endogenous Metabolite (1) Endothelin Receptor (1) Glycosidase (1) Reactive Oxygen Species (ROS) (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cancer (3) Infection (10)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Peptides

Natural
Products

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W052289

Methyl 6-bromo-1H-indole-3-carboxylate	Endogenous Metabolite	Cancer
Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with antitumor activity. Methyl 6-bromo-1H-indole-3-carboxylate showed growth inhibition against Staphylococcus epidermidis, exhibiting weak or moderate minimum inhibitory concentrations (MICs) .

HY-RS29045

Ghitm Rat Pre-designed siRNA Set A MICS1	Small Interfering RNA (siRNA)	Others
Ghitm Rat Pre-designed siRNA Set A contains three designed siRNAs for Ghitm gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ghitm Rat Pre-designed siRNA Set A Ghitm Rat Pre-designed siRNA Set A

HY-RS22524

Ghitm Mouse Pre-designed siRNA Set A MICS1; PTD010; Tmbim5; 1010001P14Rik	Small Interfering RNA (siRNA)	Others
Ghitm Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ghitm gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ghitm Mouse Pre-designed siRNA Set A Ghitm Mouse Pre-designed siRNA Set A

HY-RS05411

GHITM Human Pre-designed siRNA Set A DERP2; MICS1; My021; PTD010; TMBIM5; HSPC282	Small Interfering RNA (siRNA)	Others
GHITM Human Pre-designed siRNA Set A contains three designed siRNAs for GHITM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

GHITM Human Pre-designed siRNA Set A GHITM Human Pre-designed siRNA Set A

HY-129454

TPU-0037A Antibiotic TPU-0037-A	Antibiotic	Infection
TPU-0037A is an antibiotic and a congener of lydicamycin. It inhibits the growth of Gram-positive bacteria, including methicillin-resistant S. aureus (MRSA), B. subtilis, and M. luteus (MICs=1.56-12.5 μg/mL), but not Gram-negative E. coli, P. mirabilis, P. vulgaris, or P. aeruginosa strains (MICs=>50 μg/mL).

HY-N8470

Steffimycin B NSC 204855; U 40615	Bacterial	Infection
Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces. It binds to DNA, preferentially intercalating at sites containing cytosine and guanine.2 Steffimycin B is cytotoxic to MCF-7, KB, NCI-H187, and Vero cells (IC₅₀s=3.5, 6.75, 3.28, and 10.5 μM, respectively). It is active against M. tuberculosis (MIC=5.2 nM), B. cereus (MIC=1.56 μg/mL), and P. falciparum (IC₅₀=2.19 μM).

HY-162451

Antibacterial agent 207	Bacterial Reactive Oxygen Species (ROS) Glycosidase	Infection
Antibacterial agent 207 (Compound Ru1) has antibacterial activity against S. aureus (MIC: 1 μg/mL), and low resistance frequencies. Antibacterial agent 207 destroys the bacterial cell membrane, promote production of ROS in bacteria .

HY-N15179

Minosaminomycin	Antibiotic Bacterial	Infection
Minosaminomycin is an antibiotic containing myo-inosamine that can be extracted from Streptomyces No. MA514A1. Minosaminomycin exerts antimicrobial activity against Mycobacterium smegrnatis ATCC 607 and Mycobacterium phlei (MIC= 1.56/6.25 mcg/mL) .

HY-W781265

BE 24566B L-755,805	Endothelin Receptor Bacterial	Infection
BE 24566B is a polyketide fungal metabolite originally isolated from S. violaceusniger. It is active against B. subtilis, B. cereus, S. aureus, M. luteus, E. faecalis, and S. thermophilus (MICs=1.56, 1.56, 1.56, 1.56, 3.13, and 3.13 μg/mL, respectively). BE 24566B is an endothelin (ET) receptor antagonist (IC₅₀s=11 and 3.9 μM for ETA and ETB receptors, respectively).

HY-P5580

Dermaseptin-B3	Bacterial	Infection Cancer
Dermaseptin-B3 inhibits the growth of Gram-positive and Gram-negative bacteria (MIC: 1.3, 2.3, 5.0, 2.6, 2.3 μM for S. aureus, P. aeruginosa, P. aeruginosa, E. (ATCC 25922), E. (54127) respectively). Dermaseptin-B3 also inhibits tumor cell proliferation .

HY-130596

DC-86-M	Antibiotic Bacterial	Infection Cancer
DC-86-M is an antibiotic, which can be isolated from Streptomyces luteogriseus. DC-86-M exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Vibrio anguillarum, and Proteus vulgaris, with *MIC* <1 μg/mL. DC-86-M exhibits antitumor activity against mouse sarcoma 180 with LD₅₀ of 25 mg/kg .

HY-N8301

Ilicicolin F LL-Z 1272ζ	Bacterial	Infection
Ilicicolin F is a fungal metabolite that has been found in Fusarium and has diverse biological activities. It inhibits T. vivax alternative oxidase and the E. coli ubiquinol oxidase cytochrome bo (IC₅₀s=0.43 and 0.37 μM, respectively) but not the E. coli ubiquinol oxidase cytochrome bd (IC₅₀=85 μM).2 Ilicicolin F is active against the fungi A. fumigatus and C. albicans (MICs=1.66-3.33 and 6.66-13.33 μg/mL, respectively). It is cytotoxic to HeLa cells with an EC₅₀ value of 0.003 μg/mL.

HY-155511

DprE1-IN-6	Bacterial	Infection
DprE1-IN-6 (Compound 56) is a DprE1 inhibitor. DprE1-IN-6 has anti-TB activity against Mtb H37Rv strain (MIC: 1 μM). DprE1-IN-6 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-6 has high microsomal stability and medium clearance .

HY-155512

DprE1-IN-7	Bacterial	Infection
DprE1-IN-7 (Compound 64) is a DprE1 inhibitor. DprE1-IN-7 has anti-TB activity against Mtb H37Rv strain (MIC: 1 μM). DprE1-IN-7 also has antimycobacterial activity against drug-resistant strains. DprE1-IN-7 has high microsomal stability and medium clearance .

Cat. No.	Product Name	Target	Research Area

HY-P5580

Dermaseptin-B3	Bacterial	Infection Cancer
Dermaseptin-B3 inhibits the growth of Gram-positive and Gram-negative bacteria (MIC: 1.3, 2.3, 5.0, 2.6, 2.3 μM for S. aureus, P. aeruginosa, P. aeruginosa, E. (ATCC 25922), E. (54127) respectively). Dermaseptin-B3 also inhibits tumor cell proliferation .

Methyl 6-bromo-1H-indole-3-carboxylate	Structural Classification Alkaloids Marine natural products Source classification Sponge Indole Alkaloids	Endogenous Metabolite
Methyl 6-bromo-1H-indole-3-carboxylate is a marine-derived natural product with antitumor activity. Methyl 6-bromo-1H-indole-3-carboxylate showed growth inhibition against Staphylococcus epidermidis, exhibiting weak or moderate minimum inhibitory concentrations (MICs) .

Minosaminomycin	Structural Classification Microorganisms Antibiotics Source classification	Antibiotic Bacterial
Minosaminomycin is an antibiotic containing myo-inosamine that can be extracted from Streptomyces No. MA514A1. Minosaminomycin exerts antimicrobial activity against Mycobacterium smegrnatis ATCC 607 and Mycobacterium phlei (MIC= 1.56/6.25 mcg/mL) .

DC-86-M	Structural Classification Microorganisms Antibiotics Source classification Disease Research Anticancer	Antibiotic Bacterial
DC-86-M is an antibiotic, which can be isolated from Streptomyces luteogriseus. DC-86-M exhibits antibacterial activities against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Vibrio anguillarum, and Proteus vulgaris, with *MIC* <1 μg/mL. DC-86-M exhibits antitumor activity against mouse sarcoma 180 with LD₅₀ of 25 mg/kg .

Ghitm Rat Pre-designed siRNA Set A MICS1		siRNAs Rat Pre-designed siRNA Sets
Ghitm Rat Pre-designed siRNA Set A contains three designed siRNAs for Ghitm gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Ghitm Mouse Pre-designed siRNA Set A MICS1; PTD010; Tmbim5; 1010001P14Rik		siRNAs Mouse Pre-designed siRNA Sets
Ghitm Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ghitm gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

GHITM Human Pre-designed siRNA Set A DERP2; MICS1; My021; PTD010; TMBIM5; HSPC282		siRNAs Human Pre-designed siRNA Sets
GHITM Human Pre-designed siRNA Set A contains three designed siRNAs for GHITM gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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