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Results for "

MG 2

" in MedChemExpress (MCE) Product Catalog:

10

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Recombinant Proteins

3

Antibodies

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-164220
    PPM1A-IN-1

    		Phosphatase Bacterial Infection
    PPM1A-IN-1 (Compound IV-4) is an inhibitor for PP2C Ser/Thr phosphatase protein phosphatase Mg2+/Mn2+-dependent 1A. PPM1A-IN-1 exhibits antibacterial activity against Mycobacterium tuberculosis .
    PPM1A-IN-1
  • HY-126220A
    KMG-301AM TFA

    		Fluorescent Dye Others
    KMG-301AM TFA is the acetoxy methyl esterified form of KMG-301. KMG-301AM TFA successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg 2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg 2+ transport across the mitochondrial membrane in the early phases of a cellular model .
    KMG-301AM TFA
  • HY-RS08847
    MUC7 Human Pre-designed siRNA Set A

    MG2

    		 Small Interfering RNA (siRNA) Others

    MUC7 Human Pre-designed siRNA Set A contains three designed siRNAs for MUC7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MUC7 Human Pre-designed siRNA Set A
    MUC7 Human Pre-designed siRNA Set A
  • HY-RS08244
    MCOLN1 Human Pre-designed siRNA Set A

    ML1; ML4; LECD; MG-2; MLIV; MST080; TRPML1; MSTP080; TRP-ML1; TRPM-L1

    		 Small Interfering RNA (siRNA) Others

    MCOLN1 Human Pre-designed siRNA Set A contains three designed siRNAs for MCOLN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    MCOLN1 Human Pre-designed siRNA Set A
    MCOLN1 Human Pre-designed siRNA Set A
  • HY-157998
    mG2N001

    		mGluR Src Others
    mG2N001 is a negative allosteric modulator (NAM) (IC50: 93 nM) of the metabotropic glutamate receptor mGluR2 and binds to mGluR2 as an antagonist (Ki: 63 nM). mG2N001 is microparticle- and plasma-stable, and its radioisotope [11C]mG2N001 can be used in PET imaging. [11C]mG2N001 has good brain heterogeneity and brain penetration, and can selectively accumulate in mGluR2-rich regions, producing high-contrast brain images .
    mG2N001
  • HY-120459
    Rs-029

    		Na+/K+ ATPase Others
    Rs-029 is an inhibitor Na+/K+ ATPase and an activator for Mg2+ ATPase. Rs-029 decreases the ATP level in red blood cells .
    Rs-029
  • HY-D0157
    ZnAF-2

    		Biochemical Assay Reagents Others
    ZnAF-2, 6-iso- is a cell-impermeable compound that acts as a high-affinity Zn2 -specific fluorescent probe (Kd = 2.7 nM). It exhibits low basal fluorescence with an approximately 51-fold increase in fluorescence intensity upon stoichiometric (1:1) binding to Zn2 . Little affinity for Ca2 , Mg2 , Na or K .
    ZnAF-2
  • HY-138035
    Tenellin

    		Fungal Infection
    Tenellin is a fungal metabolite that has been found in Beauveria. It inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in equine erythrocytes by 51, 57, and 74%, respectively, when used at a concentration of 200 μg/mL.1 Tenellin is cytotoxic to Sf9 and Sf21 insect cells with 50% cytotoxic concentration (CC50) values of- 4.84 and 11.95 μM, respectively.
    Tenellin
  • HY-173084
    BRD6257

    		Phosphatase MDM-2/p53 Cancer
    BRD6257 is an orally active inhibitor for protein phosphatase, Mg2+/Mn2+ dependent 1D PPM1D with an IC50 of 5 nM. BRD6257 activates p53 signaling pathway with an EC50 of 51 nM, increases the p21 expression, inhibits the proliferation of cancer cell MOLM13 (IC50=2.8 μM). BRD6257 exhibits good metabolic stability in human and rat liver microsomes .
    BRD6257
  • HY-126220
    KMG-301AM

    		Fluorescent Dye Others
    KMG-301AM is the acetoxy methyl esterified form of KMG-301. KMG-301AM successfully accumulates in mitochondria and then it is hydrolyzed to KMG-301. KMG-301 is an Mg 2+-selective fluorescent probe functional in mitochondria in intact cells. Since the mitochondrial membrane is impermeable to KMG-301, it is not released upon depolarization of the mitochondrial membrane potential. KMG-301 can indicate changes in mitochondrial Mg2+ concentration and shows Mg 2+ transport across the mitochondrial membrane in the early phases of a cellular model .
    KMG-301AM

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