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Results for "

LCZ 696

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Natural
Products

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18204A
    Sacubitril/Valsartan
    Maximum Cited Publications
    8 Publications Verification

    LCZ696

    		 Angiotensin Receptor Neprilysin Apoptosis Cardiovascular Disease Endocrinology Cancer
    Sacubitril/Valsartan (LCZ696), comprised Valsartan and Sacubitril (AHU377) in 1:1 molar ratio, is a first-in-class, orally bioavailable, and dual-acting angiotensin receptor-neprilysin (ARN) inhibitor for hypertension and heart failure . Sacubitril/Valsartan ameliorates diabetic cardiomyopathy by inhibiting inflammation, oxidative stress and apoptosis .
    Sacubitril/Valsartan
  • HY-15407A
    Sacubitril hemicalcium salt
    2 Publications Verification

    AHU-377 hemicalcium salt

    		 Neprilysin Cardiovascular Disease
    Sacubitril hemicalcium salt (AHU-377 hemicalcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696.
    Sacubitril hemicalcium salt
  • HY-15407S
    Sacubitril-d4

    AHU-377-d4

    		 Neprilysin Cardiovascular Disease
    Sacubitril-d4 is the deuterium labeled Sacubitril. Sacubitril (AHU-377) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril (AHU-377) is a component of the heart failure medicine LCZ696.
    Sacubitril-d4
  • HY-15407
    Sacubitril
    2 Publications Verification

    AHU-377

    		 Neprilysin Infection Cardiovascular Disease
    Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19 .
    Sacubitril
  • HY-15407B
    Sacubitril sodium
    2 Publications Verification

    AHU-377 sodium

    		 Neprilysin Infection Cardiovascular Disease
    Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 .
    Sacubitril sodium
  • HY-15407AS
    Sacubitril-13C4 hemicalcium salt

    AHU-377-13C4 hemicalcium salt

    		 Isotope-Labeled Compounds Neprilysin Cardiovascular Disease
    Sacubitril- 13C4 (hemicalcium salt) is a 13C-labeled and deuterium labeled Sacubitril hemicalcium salt. Sacubitril (AHU-377) hemicalcium salt is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696 .
    Sacubitril-13C4 hemicalcium salt
  • HY-15407R
    Sacubitril (Standard)

    		Neprilysin Infection Cardiovascular Disease
    Sacubitril (Standard) is the analytical standard of Sacubitril. This product is intended for research and analytical applications. Sacubitril (AHU-377) is a potent and orally active NEP (neprilysin) inhibitor with an IC50 of 5 nM. Sacubitril is a component of the heart failure medicine LCZ696. Sacubitril can be used for the research of heart failure, hypertension and COVID-19 .
    Sacubitril (Standard)
  • HY-B1746R
    Pyridoxamine 5′-phosphate (Standard)

    		Reference Standards Endogenous Metabolite Neurological Disease
    Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium). This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 .
    Pyridoxamine 5′-phosphate (Standard)
  • HY-15407BR
    Sacubitril sodium (Standard)

    AHU-377 sodium (Standard)

    		 Reference Standards Neprilysin Infection Cardiovascular Disease
    Sacubitril (sodium) (Standard) is the analytical standard of Sacubitril (sodium). This product is intended for research and analytical applications. Sacubitril sodium is a potent and orally active NEP (neprilysin) inhibitor, with an IC50 of 5 nM. Sacubitril sodium enhances the tone of the natriuretic peptide (NP) system and exerts significant antihypertensive effects. Sacubitril sodium is a component of the heart failure medicine LCZ696. Sacubitril sodium can be used for the research of heart failure, hypertension and COVID-19 .
    Sacubitril sodium (Standard)

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