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Hydroxylamine

" in MedChemExpress (MCE) Product Catalog:

26

Inhibitors & Agonists

1

Biochemical Assay Reagents

8

Peptides

1

Natural
Products

5

Isotope-Labeled Compounds

2

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-Y0882
    Hydroxylamine hydrochloride

    		Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of organic synthesis .
    Hydroxylamine hydrochloride
  • HY-W000438
    N-Boc-O-tosyl hydroxylamine

    		Amino Acid Derivatives Cancer
    N-Boc-O-tosyl hydroxylamine is used as a safe and efficient nitrogen source for the N-amination of aryl and alkyl amines .
    N-Boc-O-tosyl hydroxylamine
  • HY-W012469
    O-(4-Nitrobenzyl)hydroxylamine hydrochloride

    		Biochemical Assay Reagents Others
    O-(4-Nitrobenzyl)hydroxylamine hydrochloride is a biochemical assay reagent used for the preparation of N-(4-nitrobenzyloxy)-amino acid as substrates for an unambiguous N-hydroxypeptide synthesis.
    O-(4-Nitrobenzyl)hydroxylamine hydrochloride
  • HY-Y0882R
    Hydroxylamine hydrochloride (Standard)

    		Reference Standards Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine (hydrochloride) (Standard) is the analytical standard of Hydroxylamine (hydrochloride). This product is intended for research and analytical applications. Hydroxylamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxylamine hydrochloride is an intermediate of organic synthesis .
    Hydroxylamine hydrochloride (Standard)
  • HY-Y0882S1
    Hydroxylamine-d3 hydrochloride

    		Monoamine Oxidase Cardiovascular Disease
    Hydroxylamine-d3 (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride . Hydroxyamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxyamine hydrochloride is an intermediate of organic synthesis .
    Hydroxylamine-d3 hydrochloride
  • HY-137155
    Dapsone hydroxylamine

    DDS-NOH

    		 Reactive Oxygen Species (ROS) Inflammation/Immunology
    Dapsone hydroxylamine (DDS-NOH) induces methemoglobinemia. Dapsone hydroxylamine inhibits catalase (CAT) activity and reactive oxygen species generation. Dapsone hydroxylamine also has anti-inflammatory activity .
    Dapsone hydroxylamine
  • HY-W011938S
    O-((Perfluorophenyl)methyl)hydroxylamine-d2 hydrochloride

    		Isotope-Labeled Compounds Others
    O-((Perfluorophenyl)methyl)hydroxylamine-d2 (hydrochloride) is the deuterium labeled O-((Perfluorophenyl)methyl)hydroxylamine hydrochloride .
    O-((Perfluorophenyl)methyl)hydroxylamine-d2 hydrochloride
  • HY-137155S
    Dapsone hydroxylamine-d4

    DDS-NOH-d4

    		 Isotope-Labeled Compounds Others
    Dapsone hydroxylamine-d4 is the deuterium labeled Dapsone hydroxylamine .
    Dapsone hydroxylamine-d4
  • HY-W722122
    N-(1-(Adamantan-1-yl)ethyl)hydroxylamine-d4

    N-(1-((3r,5r,7r)-Adamantan-1-yl)ethyl)Hydroxylamine-d4

    		 Isotope-Labeled Compounds Others
    N-(1-(Adamantan-1-yl)ethyl)hydroxylamine-d4 (N-(1-((3r,5r,7r)-Adamantan-1-yl)ethyl)hydroxylamine-d4) is the deuterium labeled N-(1-(adamantan-1-yl)ethyl)hydroxylamine (HY-75864).
    N-(1-(Adamantan-1-yl)ethyl)hydroxylamine-d4
  • HY-W073314
    2,2,2-Trifluoroethoxyamine hydrochloride

    O-(2,2,2-Trifluoroethyl)Hydroxylamine hydrochloride

    		 Biochemical Assay Reagents Others
    2,2,2-Trifluoroethoxyamine (O-(2,2,2-Trifluoroethyl)hydroxylamine) hydrochloride can be used as an oxime reactant for coupling reactions with reducing sugars .
    2,2,2-Trifluoroethoxyamine hydrochloride
  • HY-106429
    OT-551 free base

    		Reactive Oxygen Species (ROS) Others
    OT-551 (free base) is a lipophilic, disubstituted hydroxylamine with antioxidant properties. OT-551 can be used as an eye drop and can be converted by intraocular esterases to its active metabolite, Tempol-H (TP-H). OT-551 can be utilized in geographic atrophy and macular degeneration research .
    OT-551 free base
  • HY-156846
    O-Benzoylhydroxylamine

    		Dipeptidyl Peptidase Metabolic Disease
    O-Benzoyl hydroxylamine is a DPP-IV inhibitor with anti-diabetic effects (WO2006034435A2) .
    O-Benzoylhydroxylamine
  • HY-13543
    Tretazicar

    CB 1954

    		 Quinone Reductase DNA Alkylator/Crosslinker Cancer
    Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) .
    Tretazicar
  • HY-13543R
    Tretazicar (Standard)

    		DNA Alkylator/Crosslinker Cancer
    Tretazicar (Standard) is the analytical standard of Tretazicar. This product is intended for research and analytical applications. Tretazicar (CB 1954), an antitumor proagent, is highly selective against the Walker 256 rat tumour line. Tretazicar is enzymatically activated to generate a bifunctional agent, which can form DNA-DNA interstrand cross-links. Tretazicar in rat cells involves the reduction of its 4-nitro group to a 4-hydroxylamine by the enzyme NAD(P)H:quinone oxidoreductase 1 (NQO1) .
    Tretazicar (Standard)
  • HY-W591965
    t-Boc-aminooxy-pentane-amine

    		Biochemical Assay Reagents Others
    t-Boc-Aminooxy-pentane-amine is a linker containing an aminooxy group and a primary amine. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    t-Boc-aminooxy-pentane-amine
  • HY-W800650
    Aminooxy-PEG1-amine

    		Biochemical Assay Reagents Others
    Aminooxy-PEG1-amine is a chemical reagent containing an aminooxy group and a primary amine. The aminooxy group is reactive with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive withactivated NHS esters, or carboxylic acid in the presence of coupling reagent EDC. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term.
    Aminooxy-PEG1-amine
  • HY-147384
    CXL-1020

    		Calcium Channel Cardiovascular Disease
    CXL-1020 is a hydroxylamine-based nitroxyl (HNO) donor. CXL-1020 improves cardiac inotropy/lusitropy and Ca 2+ cycling in rats with abnormal relaxation. CXL-1020 induces vasorelaxation and improves cardiac function in canine models. CXL-1020 has been used to research systolic heart failure and stable heart failure .
    CXL-1020
  • HY-Y1860S
    Benzyloxyamine-d5

    O-BenzylHydroxylamine-d5; O-(Phenylmethyl)Hydroxylamine-d5

    		 Isotope-Labeled Compounds Others
    Benzyloxyamine-d5 (O-Benzylhydroxylamine-d5) is a deuterium labeled Benzyloxyamine.
    Benzyloxyamine-d5
  • HY-W800649
    Aminooxy-PEG2-amine hydrochloride

    		Biochemical Assay Reagents Others
    Aminooxy-PEG2-amine hydrochloride (compound L3) is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term .
    Aminooxy-PEG2-amine hydrochloride
  • HY-125586
    β-Amanitin

    		DNA/RNA Synthesis ADC Cytotoxin Cancer
    β-Amanitin is a cyclic peptide toxin in the poisonous Amanita phalloides mushroom. β-Amanitin inhibits inhibits eukaryotic RNA polymerase II and III. β-Amanitin inhibits protein synthesis. β-Amanitin can be used as a cytotoxic component of antibody-drug conjugates (ADCs) .
    β-Amanitin
  • HY-158104
    LPPM-8

    		ATF6 Others
    LPPM-8 is a ligand of Med25 and an inhibitor of Med25 protein-protein interactions (PPIs). LPPM-8 engages Med25 through interaction with the H2 face of its Activator Interaction Domain and stabilizes full-length protein in the cellular proteome. LPPM-8 is an orthosteric inhibitor of H2-binding transcriptional activators (such as ATF6a). LPPM-8 can be used for studying Med25 and Mediator complex biology .
    LPPM-8
  • HY-P3100
    Orfamide A

    		Parasite Infection
    Orfamide A is a major metabolite of insecticidal biosurfactant in Pseudomonas sp. F6 and has aphidicidal activity. Orfamide A can be used for aphid control in organic agriculture. Orfamide A exhibits dose-dependent mortality against aphids with an LC50 value of 34.5 μg/mL .
    Orfamide A
  • HY-151787
    Fmoc-L-Lys(N3-Aca-DIM)-OH

    		ADC Linker Others
    Fmoc-L-Lys(N3-Aca-DIM)-OH is a click chemistry reagent containing an azide group. Used as a SPPS building-block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Lys(N3-Aca-DIM)-OH
  • HY-151786
    Fmoc-L-Lys(Pentynoyl-DIM)-OH

    		ADC Linker Others
    Fmoc-L-Lys(Pentynoyl-DIM)-OH is a click chemistry reagent containing an azide. Fmoc-L-Lys(Pentynoyl-DIM)-OH can be used as a SPPS building block for the “helping hand” strategy for purification of highly insoluble peptides. Solubilizing residues are attached to the Lys side-chains using Click-chemistry. The solubilizing tag can be removed with 1M hydrazine or hydroxylamine solution . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-L-Lys(Pentynoyl-DIM)-OH
  • HY-P10447
    Plipastatin A1

    Fengycin IX; SNA-60-367-3

    		 Phospholipase Inflammation/Immunology
    Plipastatin A1 is a lipopeptide with enzyme inhibitory and immunosuppressive activities. Plipastatin A1 is found in Bacillus cereus and inhibits phospholipase A2 (PLA2), PLC, and PLD .
    Plipastatin A1
  • HY-17365
    Octreotide acetate
    10+ Cited Publications

    SMS 201-995 acetate

    		 Somatostatin Receptor Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
    Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.
    Octreotide acetate

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