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Isoforms Recommended: HIV-1
Results for "

HIV-1 YU2

" in MedChemExpress (MCE) Product Catalog:
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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-146339
    HIV-1 inhibitor-27

    		HIV Infection Inflammation/Immunology
    HIV-1 inhibitor-27 (compound 5) is a potent HIV-1 inhibitor with IC50s of 16 μM, 0.5 μM and 0.39 μM for HIV-1 YU2, NL4-3 and 89.6 strain, respectively. HIV-1 inhibitor-27 has low cytotoxicity with a CC50 of 128 μM in TZM-bl cells. HIV-1 inhibitor-27 can be used for researching AIDS [1].
    HIV-1 inhibitor-27
  • HY-107401
    Ancriviroc

    SCH-351125

    		 HIV CCR Infection
    Ancriviroc (SCH-351125) is an orally active CCR5 antagonist. Ancriviroc has a broad-spectrum antiviral activity against HIV-1 isolates using CCR5 as their entry coreceptor (such as ASM 80, 92US715 and YU-2) with IC50s of 0.4-9 nM. Ancriviroc strongly inhibits the replication of R5-using HIV-1 isolates in SCID-hu Thy/Liv mice model of HIV-1 infection. Ancriviroc can be used for HIV infection research [1].
    Ancriviroc
  • HY-146338
    RPR103611

    		HIV Infection
    RPR103611, the betulinic acid derivative, is a potent HIV-1 entry inhibitor with IC50s of 80, 0.27, and 0.17 for CCR5-tropic virus YU2, CXCR4-tropic virus NL4-3 and dual tropic virus 89.6, respectively [1].
    RPR103611

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