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GPI-1046

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-124619
    GPI-1046

    		EAAT HIV Neurological Disease
    GPI-1046 is an orally active, antibiotic-free immunophilin ligand that reduces ethanol intake by upregulating glutamate transporter 1 (GLT1) in the prefrontal cortex (PFC) and nucleus accumbens core (NAc-core). GPI-1046 improves human immunodeficiency virus (HIV)-associated sensory neuropathy (HIV-SN) by attenuating store-operated calcium (SOC) entry. GPI-1046 has neuroprotective activity .
    GPI-1046

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