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GI transit

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145404
    Mitragynine pseudoindoxyl

    		Opioid Receptor Metabolic Disease
    Mitragynine pseudoindoxyl is a potent MOR agonist. Mitragynine pseudoindoxyl displays reduced hyperlocomotion, inhibition of GI transit and reinforcing properties .
    Mitragynine pseudoindoxyl
  • HY-B0194
    Tizanidine

    		Adrenergic Receptor Neurological Disease Endocrinology Cancer
    Tizanidine is an orally active, imidazoline central α2-adrenoceptor agonist (IC50 = 6.9 nmol), which can be used to manage spasticity secondary to conditions such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI). Tizanidine is a centrally acting skeletal muscle relaxant. Tizanidine reduces the release of the excitatory amino acids glutamate and aspartate from the presynaptic terminal of spinal interneurons. Tizanidine reduces tonic stretch reflexes and polysynaptic reflex activity in spinal transected cat model. Tizanidine can decrease blood pressure and heart rate in animal models. Tizanidine possesses antinociceptive activity and inhibits gastrointestinal (GI) transit .
    Tizanidine
  • HY-B0194R
    Tizanidine (Standard)

    		Reference Standards Adrenergic Receptor Neurological Disease Endocrinology Cancer
    Tizanidine (Standard) is the analytical standard of Tizanidine. This product is intended for research and analytical applications. Tizanidine is an orally active, imidazoline central α2-adrenoceptor agonist (IC50 = 6.9 nmol), which can be used to manage spasticity secondary to conditions such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI). Tizanidine is a centrally acting skeletal muscle relaxant. Tizanidine reduces the release of the excitatory amino acids glutamate and aspartate from the presynaptic terminal of spinal interneurons. Tizanidine reduces tonic stretch reflexes and polysynaptic reflex activity in spinal transected cat model. Tizanidine can decrease blood pressure and heart rate in animal models. Tizanidine possesses antinociceptive activity and inhibits gastrointestinal (GI) transit .
    Tizanidine (Standard)

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