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Results for "

F1Fo-ATP synthase

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162142
    BB2-50F

    		Bacterial Succinate Dehydrogenase Reactive Oxygen Species (ROS) Infection
    BB2-50F, a potent M. tuberculosis inhibitor, is a succinate dehydrogenase and F1Fo-ATP synthase inhibitor. BB2-50F rapidly sterilizes both replicating and non-replicating cultures of M. tuberculosis. BB2-50F inhibits succinate oxidation, decreases the activity of the tricarboxylic acid (TCA) cycle, and results in succinate secretion from M. tuberculosis. BB2-50F induces reactive oxygen species (ROS) in M. tuberculosis .
    BB2-50F
  • HY-112715
    ATP synthase inhibitor 1

    		ATP Synthase Cardiovascular Disease
    ATP synthase inhibitor 1 is a potent inhibitor of c subunit of the F1/FO-ATP synthase complex, inhibits mitochondrial permeability transition pore (mPTP) opening, does not affect ATP levels .
    ATP synthase inhibitor 1
  • HY-14881
    Bedaquiline
    40+ Cited Publications

    TMC207; R207910

    		 Bacterial Antibiotic Infection
    Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
    Bedaquiline
  • HY-14881S1
    (Rac)-Bedaquiline-d6

    		Isotope-Labeled Compounds Bacterial Antibiotic Others
    (Rac)-Bedaquiline-d6 is the deuterium labeled Bedaquiline (HY-14881) . Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
    (Rac)-Bedaquiline-d6
  • HY-14881B
    (Rac)-Bedaquiline

    (Rac)-TMC207; (Rac)-R207910

    		 Bacterial Infection
    (Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
    (Rac)-Bedaquiline
  • HY-14881R
    Bedaquiline (Standard)

    TMC207 (Standard); R207910 (Standard)

    		 Reference Standards Bacterial Antibiotic Infection
    Bedaquiline (Standard) is the analytical standard of Bedaquiline. This product is intended for research and analytical applications. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
    Bedaquiline (Standard)
  • HY-14881S2
    Bedaquiline impurity 2-d6

    		Isotope-Labeled Compounds Bacterial Antibiotic Infection
    Bedaquiline impurity 2-d6 is deuterium labeled Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit . Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis .
    Bedaquiline impurity 2-d6

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