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DIOA

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-137148
    DIOA

    		Chloride Channel Cancer
    DIOA is a potent acid-sensitive outwardly rectifying (ASOR) anion channel antagonist .
    DIOA
  • HY-172533
    3′,5′-DiOA-dC

    		STING Cancer
    3’,5’-DiOA-dC is a hydrophobic nucleotide lipid and a ligand for the STING agonist c-di-GMP (CDG). 3’,5’-DiOA-dC can assemble with CDG and form stable cyclic dinucleotide nanoparticles via various supramolecular forces driven by molecular recognition. 3’,5’-DiOA-dC can decrease tumor weight and volume, increase CD8 T cell, neutrophils as well as NK cell counts in tumor microenvironment in combination with CDG. 3’,5’-DiOA-dC also increases the levels of TNF-α and IFN-γ in murine melanoma model .
    3′,5′-DiOA-dC

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