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Results for "

CYP1A2 substrates

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

1

Fluorescent Dye

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0144
    Resorufin methyl ether

    Methoxyresorufin

    		 Cytochrome P450 Others
    Resorufin methyl ether (Methoxyresorufin) is a cytochrome P450 fluorometric substrate . Resorufin methyl ether is a relatively specific substrate for CYP1A2 activity in rodents .
    Resorufin methyl ether
  • HY-W267897
    7-Benzyloxy-4-(trifluoromethyl)coumarin

    7-BFC

    		 Cytochrome P450 Others
    7-Benzyloxy-4-(trifluoromethyl)coumarin (7-BFC) is a coumarin fluorescent substrate. 7-Benzyloxy-4-(trifluoromethyl)coumarin is a substrate for cDNA-expressed CYP1A2 and CYP3A4 and is metabolized to 7-hydroxy-4-trifluoromethylcoumarin (HFC). 7-Benzyloxy-4-(trifluoromethyl)coumarin is used for rapid CYP isoform metabolism and inhibition screening studies .
    7-Benzyloxy-4-(trifluoromethyl)coumarin
  • HY-111338
    Tacrine
    5 Publications Verification

    		 Cholinesterase (ChE) Neurological Disease
    Tacrine is an effective oral acetylcholine (AChE) inhibitor (IC50 = 109 nM) and also acts as an active substrate for CYP1A2. Tacrine can restore cognitive dysfunction in elderly rats. Tacrine can cause liver toxicity and is used in research related to Alzheimer's disease .
    Tacrine
  • HY-124158
    KR-60436

    		Proton Pump Metabolic Disease
    KR-60436 is a reversible H +/K +-ATPase inhibitor. KR-60436 can potently inhibit the metabolism of CYP1A2 substrates .
    KR-60436
  • HY-E70476
    Human CYP1B1,Low-Reductase

    		Cytochrome P450 Metabolic Disease
    Human CYP1B1, Low-Reductase, a recombinant CYP1B1, is a member of the CYP enzyme family. CYP1B1 is constitutively expressed at some extrahepatic tissues, metabolizes a variety of the same, mostly planar, substrates for CYP1A1 and CYP1A2 .
    Human CYP1B1,Low-Reductase

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