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CETP+Inhibitors

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-18778
    Obicetrapib

    TA-8995; DEZ-001

    		 CETP Metabolic Disease
    TA-8995 is a new and selective cholesteryl ester transfer protein (CETP) inhibitor.
    Obicetrapib
  • HY-13327
    Evacetrapib
    2 Publications Verification

    LY2484595

    		 CETP Cardiovascular Disease
    Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein (IC50 5.5 nM) and CETP activity in human plasma (IC50 36 nM) in vitro.
    Evacetrapib
  • HY-116078
    CKD-519

    		CETP Cardiovascular Disease
    CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor, which inhibits CETP-mediated transfer of cholesteryl ester in human serum with an IC50 of 2.3 nM .
    CKD-519
  • HY-12090
    Anacetrapib
    3 Publications Verification

    MK-0859

    		 PCSK9 Cardiovascular Disease
    Anacetrapib is a potent CETP inhibitor, with IC50s of 7.9±2.5 nM and 11.8±1.9 nM for rhCETP and C13S CETP mutant, respectively.
    Anacetrapib
  • HY-12089
    Torcetrapib

    CP-529414

    		 CETP Endocrinology
    Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein (CETP) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM .
    Torcetrapib
  • HY-14950
    Dalcetrapib

    JTT-705; RO4607381

    		 CETP Cardiovascular Disease Cancer
    Dalcetrapib (JTT-705) is an orally active cholesteryl ester transfer protein (CETP) inhibitor with IC50s of 204.6 nM and 6 μM against recombinant human (rh) CETP and human plasma CETP, respectively .
    Dalcetrapib
  • HY-142643
    CETP-IN-4

    		CETP Metabolic Disease
    CETP-IN-4 is a cholesteryl ester transfer protein (CETP) inhibitor.
    CETP-IN-4
  • HY-107997
    TAP311

    		CETP Cardiovascular Disease
    TAP311 is a cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 62 nM .
    TAP311
  • HY-123039
    CP-532623

    		CETP Metabolic Disease
    CP-532623 is a CETP inhibitor and elevates high-density lipoprotein cholesterolion. CP-532623 is a close structural analogue of Torcetrapib. CP-532623 has highly lipophilic properties .
    CP-532623
  • HY-13327R
    Evacetrapib (Standard)

    		CETP Cardiovascular Disease
    Evacetrapib (Standard) is the analytical standard of Evacetrapib. This product is intended for research and analytical applications. Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein (IC50 5.5 nM) and CETP activity in human plasma (IC50 36 nM) in vitro.
    Evacetrapib (Standard)
  • HY-12090R
    Anacetrapib (Standard)

    		PCSK9 Cardiovascular Disease
    Anacetrapib (Standard) is the analytical standard of Anacetrapib. This product is intended for research and analytical applications. Anacetrapib is a potent CETP inhibitor, with IC50s of 7.9±2.5 nM and 11.8±1.9 nM for rhCETP and C13S CETP mutant, respectively.
    Anacetrapib (Standard)
  • HY-132303
    MK-8262

    		CETP Cardiovascular Disease Metabolic Disease
    MK-8262 is an orally active and potent cholesteryl ester transfer protein (CETP) inhibitor with an IC50 of 53 nM and a log D of 5.3. MK-8262, a bistrifluoromethyl analogue, has the potential for coronary heart disease (CHD) correlated high-density lipoprotein (HDL) and low-density lipoprotein (LDL) research .
    MK-8262

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