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BRL-6231

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-116387A
    WR99210 hydrochloride
    2 Publications Verification

    BRL 6231

    		 Dihydrofolate reductase (DHFR) Parasite Infection
    WR99210 hydrochloride is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 hydrochloride shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains as well as T. gondii .
    WR99210 hydrochloride
  • HY-116387
    WR99210
    2 Publications Verification

    BRL 6231 free base

    		 Dihydrofolate reductase (DHFR) Parasite Infection
    WR99210 is an orally active and low-toxicity dihydrofolate reductase (DHFR) inhibitor (IC50<0.075 nM). WR99210 shows good antiparasitic activity and is effective against P. falciparum and P. falciparum strains (including Pyrimethamine (HY-18062)-resistant P. falciparum strains) as well as T. gondii .
    WR99210

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