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Results for "

Antimalarial agent-1

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W009109
    Antimalarial agent 1

    		Parasite Infection
    Antimalarial agent 1 is a potent antimalarial agent .
    Antimalarial agent 1
  • HY-114197
    Antimalarial agent 14

    		Mitochondrial Metabolism Parasite Infection
    Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent .
    Antimalarial agent 14
  • HY-W131282
    Antimalarial agent 39

    		Parasite Infection
    Antimalarial agent 39 (compound 1) is an intermediate in the synthesis of antimalarial agents .
    Antimalarial agent 39
  • HY-111529
    Tafenoquine
    4 Publications Verification

    WR 238605

    		 Parasite Infection
    Tafenoquine (WR 238605) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent .
    Tafenoquine
  • HY-111529A
    Tafenoquine Succinate
    4 Publications Verification

    WR 238605 Succinate

    		 Parasite Infection
    Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent .
    Tafenoquine Succinate
  • HY-W072459
    6'-Hydroxydihydrocinchonidine

    		Drug Metabolite Infection
    6'-Hydroxydihydrocinchonidine is a metabolite of Quinine (HY-D0143) (antimalarial agent) .
    6'-Hydroxydihydrocinchonidine
  • HY-N15562
    Batzelladine L

    		Parasite Infection
    Batzelladine L is a potent Plasmodium falciparum inhibitor (IC50= 0.4 μM). Batzelladine L shows moderate cytotoxicity to HepG2 cells (CC50= 14 μM) with antimalarial properties. Batzelladine L is promising for research of antimalarial agents .
    Batzelladine L
  • HY-N15561
    Batzelladine F

    		Parasite Infection
    Batzelladine F is a potent Plasmodium falciparum inhibitor (IC50 3D7= 0.13 μM). Batzelladine F shows moderate cytotoxicity to HepG2 cells (CC50=10.6 μM) with antimalarial properties. Batzelladine F is promising for research of antimalarial agents .
    Batzelladine F
  • HY-111529AR
    Tafenoquine Succinate (Standard)

    		Parasite Infection
    Tafenoquine (Succinate) (Standard) is the analytical standard of Tafenoquine (Succinate). This product is intended for research and analytical applications. Tafenoquine Succinate (WR 238605 Succinate) is an 8-aminoquinoline. Tafenoquine is an anti-malarial prophylactic agent .
    Tafenoquine Succinate (Standard)
  • HY-108640
    HLI373

    		MDM-2/p53 Parasite Apoptosis Infection Cancer
    HLI373 is an efficacious Hdm2 inhibitor. HLI373 inhibits the ubiquitin ligase activity of Hdm2. HLI373 is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents . Antimalarial activity .
    HLI373
  • HY-108640A
    HLI373 dihydrochloride

    		MDM-2/p53 Parasite Apoptosis Infection Cancer
    HLI373 dihydrochloride is an efficacious Hdm2 inhibitor. HLI373 dihydrochloride inhibits the ubiquitin ligase activity of Hdm2. HLI373 dihydrochloride is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents . Antimalarial activity .
    HLI373 dihydrochloride
  • HY-116847
    Leucodelphinidin

    Leukoefdin

    		 Parasite Infection
    Leucodelphinidin (Leukoefdin) is a flavonoid found in Terminalia plants with antiplasmodial activity against Plasmodium falciparum (3D7 and Dd2 strains). Leucodelphinidin exhibits cytotoxicity (CC50>250 μg/mL) toward Vero and Raw 264.7 cells. Leucodelphinidin is promising for research of antimalarial agents .
    Leucodelphinidin
  • HY-147850
    JMI-346

    		Parasite Infection
    JMI-346 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-346 inhibits the growth of CQ S (3D7; IC50=13 µM) and CQ R (RKL-9; IC50=33 µM) strains of P. falciparum. JMI-346 has the potential to be used as an anti-malarial agent .
    JMI-346
  • HY-106005
    MMV390048
    3 Publications Verification

    		 Parasite PI4K Infection
    MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kd app=0.3 µM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent .
    MMV390048
  • HY-147849
    JMI-105

    		Parasite Infection
    JMI-105 is a potent PfFP-2 (Plasmodium falciparum falcipain-2 protease) inhibitor. JMI-105 inhibits the growth of CQ S (3D7; IC50=8.8 µM) and CQ R (RKL-9; IC50=14.3 µM) strains of P. falciparum. JMI-105 significantly decreases parasitemia and prolonged host survival in a murine model with P. berghei ANKA infection. JMI-105 has the potential to be used as an anti-malarial agent .
    JMI-105

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