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Results for "

Angelic acid

" in MedChemExpress (MCE) Product Catalog:

6

Inhibitors & Agonists

2

Natural
Products

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6929

    Others Neurological Disease Cancer
    Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .
    Angelic acid
  • HY-N6929R

    Others Neurological Disease Cancer
    Angelic acid (Standard)) is the analytical standard of Angelic acid (HY-N6929). This product is intended for research and analytical applications. Angelic acid is a ferroptosis inducer, targeting NRF2 degradation. Angelic acid binds to NRF2 protein and promotes NRF2 degradation via ubiquitination-proteasome pathway, relieves the inhibitory effect of NRF2 on oxidative stress and lipid peroxidation. Then, Angelic acid induces ferroptosis in tumor cells. Angelic acid can enhance the accumulation of intracellular reactive oxygen species (ROS), upregulate ferroptosis-related markers CHAC1 and PTGS2, and synergize with ferroptosis inducers to enhance anti-tumor effects. Angelic acid also has the activity of scavenging UVA-induced ROS in vitro, inhibiting skin fibroblast senescence and extracellular matrix degradation. Angelic Acid helps wound healing with sedative activity .
    Angelic acid (Standard)
  • HY-N6086

    Drug Derivative Others
    Angelic anhydride is an aliphatic acid anhydride from unsaturated hydrocarbon acid anhydrides .
    Angelic anhydride
  • HY-RS00685

    Small Interfering RNA (siRNA) Others

    ANGEL1 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGEL1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ANGEL1 Human Pre-designed siRNA Set A
    ANGEL1 Human Pre-designed siRNA Set A
  • HY-RS00686

    Small Interfering RNA (siRNA) Others

    ANGEL2 Human Pre-designed siRNA Set A contains three designed siRNAs for ANGEL2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    ANGEL2 Human Pre-designed siRNA Set A
    ANGEL2 Human Pre-designed siRNA Set A
  • HY-161103

    Endogenous Metabolite Cancer
    Angeloyl-CoA is a CoA-activated form of angelic acid and has anticancer activity. Angeloyl-CoA can be produced based on yeast .
    Angeloyl-CoA

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