Search Result
Results for "
Acylcarnitine
" in MedChemExpress (MCE) Product Catalog:
1
Biochemical Assay Reagents
14
Isotope-Labeled Compounds
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-130466
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Endogenous Metabolite
GlyT
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Metabolic Disease
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Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM .
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- HY-113256
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Endogenous Metabolite
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Metabolic Disease
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Linoleyl carnitine is an acylcarnitine used to study long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and fatty acid oxidation disorders in fibroblasts .
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- HY-113266
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- HY-113144
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- HY-115704
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- HY-113069
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Endogenous Metabolite
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Metabolic Disease
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Decanoylcarnitine is a fatty ester lipid and an acylcarnitine derivative, which is a metabolite associated with impaired fatty acid metabolism in the elderly population .
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- HY-145528
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Endogenous Metabolite
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Metabolic Disease
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Heptanoyl-L-carnitine chloride (trans-3,4-methylene-heptanoylcarnitine) is an acylcarnitine. Heptanoyl-L-carnitine chloride causes exercise-induced alterations in the human metabolome in plasma and skeletal muscle tissue .
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- HY-130466R
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Endogenous Metabolite
GlyT
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Metabolic Disease
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Stearoyl-L-carnitine (chloride) (Standard) is the analytical standard of Stearoyl-L-carnitine (chloride). This product is intended for research and analytical applications. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM .
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- HY-172548
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Endogenous Metabolite
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Metabolic Disease
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Docosahexaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Docosahexaenoic acid (HY-B2167) and L-carnitine (HY-B0399). Docosahexaenoyl-L-carnitine chloride is transported into mitochondria for β -oxidation and decomposition under the action of carnitine palmitoyltransferase I (CPT I) and others. Docosahexaenoyl-L-carnitine chloride is promising for research of diseases related to fatty acid metabolism .
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- HY-113261A
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GlyT
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Neurological Disease
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(Rac)-Oleoylcarnitine is an endogenous acylcarnitine and a potential noncompetitive inhibitor of glycine transporter 2 (GLYT2) that can be used as a pain suppressant.
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- HY-113266R
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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Valerylcarnitine (Standard) is the analytical standard of Valerylcarnitine. This product is intended for research and analytical applications. Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines.
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- HY-113144S
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- HY-113144R
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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L-Hexanoylcarnitine (Standard) is the analytical standard of L-Hexanoylcarnitine. This product is intended for research and analytical applications. L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease.
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- HY-W654091
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Isotope-Labeled Compounds
Others
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Others
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(R)-Butyryl carnitine-d5 chloride is deuterium labeled Butyryl-L-carnitine (chloride). Butyryl-L-carnitine chloride is an acylcarnitine that can be isolated from Plasma/Serum .
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- HY-W015300S
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Octanedioic acid-d4
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Endogenous Metabolite
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Metabolic Disease
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Suberic acid-d4 is the deuterium labeled Suberic acid . Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency .
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- HY-W015300S1
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Octanedioic acid-d12
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Endogenous Metabolite
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Metabolic Disease
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Suberic acid-d12 is the deuterium labeled Suberic acid . Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency .
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- HY-145525
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CAR 18:2; C18:2 Carnitine; L-Carnitine linoleoyl ester
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Endogenous Metabolite
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Others
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Linoleoyl-L-carnitine is a naturally occurring long-chain acylcarnitine. Hepatic levels of linoleoyl-L-carnitine are increased following high-dose (200 mg/kg) administration of Isoniazid (Item No. 20378) in mice.
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- HY-W587977
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- HY-113266S
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C5:0 L-carnitine-d9
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Isotope-Labeled Compounds
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Metabolic Disease
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Valerylcarnitine-d9 (C5:0 L-carnitine-d9) is the deuterium labeled Valerylcarnitine (HY-113266). Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines .
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- HY-W654252
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Isotope-Labeled Compounds
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Metabolic Disease
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Linoleoyl Carnitine (N-methyl-d3) is the deuterium labeled Linoleyl carnitine (HY-113256). Linoleyl carnitine is an acylcarnitine used to study long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and fatty acid oxidation disorders in fibroblasts .
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- HY-113147
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Potassium Channel
Endogenous Metabolite
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Cardiovascular Disease
Metabolic Disease
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L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .
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- HY-113147A
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Potassium Channel
Endogenous Metabolite
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Cardiovascular Disease
Metabolic Disease
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L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .
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- HY-W014787
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Sebacic acid
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Endogenous Metabolite
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Metabolic Disease
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Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency .
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- HY-130466S
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Endogenous Metabolite
GlyT
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Metabolic Disease
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Stearoyl-L-carnitine-d3 (chloride) is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM .
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- HY-113147B
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Endogenous Metabolite
Potassium Channel
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Cardiovascular Disease
Metabolic Disease
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L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine TFA inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .
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- HY-113202S1
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Isotope-Labeled Compounds
GlyT
Endogenous Metabolite
PKC
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Neurological Disease
Metabolic Disease
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Stearoyl-L-carnitine-d9 chloride is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride, a fatty ester lipid molecule, is an endogenous metabolite. Stearoyl-L-carnitine chloride can be used as PKC inhibitor. Stearoyl-L-carnitine chloride accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoyl-L-carnitine chloride inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoyl-L-carnitine chloride acts as a metabolomics biomarker for Parkinson’s disease. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2 .
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- HY-W654264
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Endogenous Metabolite
Integrin
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Cardiovascular Disease
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2-Methylbutyrylcarnitine (chloride) is a gut microbial metabolite which binds to integrin α2β1 in platelets, potentiating cytosolic phospholipase A2 (cPLA2) activation and platelet hyperresponsiveness. 2-Methylbutyrylcarnitine (chloride) enhances platelet hyperreactivity and thrombus formation in mice. 2-Methylbutyrylcarnitine (chloride) is a branched-chain acylcarnitine .
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- HY-W770914
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Isotope-Labeled Compounds
GlyT
Endogenous Metabolite
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Metabolic Disease
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Stearoyl-L-carnitine chloride- 13C3 is the 13C-labeled Stearoyl-L-carnitine chloride (HY-130466). Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM .
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- HY-113147AS
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Potassium Channel
Endogenous Metabolite
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Cardiovascular Disease
Metabolic Disease
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L-Palmitoylcarnitine-d3 hydrochloride is the deuterium labeled L-Palmitoylcarnitine hydrochloride. L-Palmitoylcarnitine hydrochloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine hydrochloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .
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- HY-158812
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Drug Derivative
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Metabolic Disease
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Eicosapentaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Eicosapentaenoic Acid (HY-B0660) and L-Carnitine (HY-B0399). The levels of Eicosapentaenoyl-L-carnitine chloride are increased in the eyes of mice fed a diet high in n-3/n-6 polyunsaturated fatty acids (PUFAs) in a mouse model of myopia induced by out-of-focus lenses .
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- HY-113147AR
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Reference Standards
Potassium Channel
Endogenous Metabolite
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Cardiovascular Disease
Metabolic Disease
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L-Palmitoylcarnitine (chloride) (Standard) is the analytical standard of L-Palmitoylcarnitine (chloride). This product is intended for research and analytical applications. L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1].
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- HY-113147S1
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- HY-152013S
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Isotope-Labeled Compounds
Endogenous Metabolite
Potassium Channel
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Cardiovascular Disease
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L-Palmitoylcarnitine-d3-1 (hydrochloride) is deuterium labeled L-Palmitoylcarnitine (chloride). L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .
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- HY-W014787S
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Endogenous Metabolite
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Metabolic Disease
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Decanedioic acid-d4 is the deuterium labeled Decanedioic acid (HY-W014787). Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency .
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- HY-W014787S1
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Endogenous Metabolite
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Metabolic Disease
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Decanedioic acid-d16 is the deuterium labeled Decanedioic acid (HY-W014787). Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency .
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- HY-W014787R
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Sebacic acid (Standard)
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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Decanedioic acid (Standard) is the analytical standard of Decanedioic acid (HY-W014787). This product is intended for research and analytical applications. Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency .
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Cat. No. |
Product Name |
Type |
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- HY-W587977
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3-Hydroxyhexadecanoylcarnitine
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Biochemical Assay Reagents
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3-Hydroxypalmitoylcarnitine (3-Hydroxyhexadecanoylcarnitine) is an acylcarnitine. Elevated levels of 3-Hydroxypalmitoylcarnitine are associated with cardiovascular disease (CVD) in type 2 diabetes mellitus (T2DM) .
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Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Cat. No. |
Product Name |
Chemical Structure |
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- HY-W654091
-
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(R)-Butyryl carnitine-d5 chloride is deuterium labeled Butyryl-L-carnitine (chloride). Butyryl-L-carnitine chloride is an acylcarnitine that can be isolated from Plasma/Serum .
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- HY-W015300S
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Suberic acid-d4 is the deuterium labeled Suberic acid . Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency .
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- HY-W015300S1
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Suberic acid-d12 is the deuterium labeled Suberic acid . Suberic acid (Octanedioic acid) is found to be associated with carnitine-acylcarnitine translocase deficiency, malonyl-Coa decarboxylase deficiency .
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- HY-130466S
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Stearoyl-L-carnitine-d3 (chloride) is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM .
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- HY-113147AS
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L-Palmitoylcarnitine-d3 hydrochloride is the deuterium labeled L-Palmitoylcarnitine hydrochloride. L-Palmitoylcarnitine hydrochloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine hydrochloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .
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- HY-113144S
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L-Hexanoylcarnitine-d9 is deuterium labeled L-Hexanoylcarnitine. L-Hexanoylcarnitine is an acylcarnitine and is found to be associated with celiac disease .
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- HY-113266S
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Valerylcarnitine-d9 (C5:0 L-carnitine-d9) is the deuterium labeled Valerylcarnitine (HY-113266). Valerylcarnitine is an endogenous metabolite, belonging to the short-chain acylcarnitines .
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- HY-W654252
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Linoleoyl Carnitine (N-methyl-d3) is the deuterium labeled Linoleyl carnitine (HY-113256). Linoleyl carnitine is an acylcarnitine used to study long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency and fatty acid oxidation disorders in fibroblasts .
|
-
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- HY-113202S1
-
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Stearoyl-L-carnitine-d9 chloride is the deuterium labeled Stearoyl-L-carnitine chloride. Stearoyl-L-carnitine chloride, a fatty ester lipid molecule, is an endogenous metabolite. Stearoyl-L-carnitine chloride can be used as PKC inhibitor. Stearoyl-L-carnitine chloride accumulates in β cells, leading to arrest of insulin synthesis and energy deficiency in type 2 diabetes mouse. Stearoyl-L-carnitine chloride inhibits lecithin cholesterol acyltransferase (LCAT) in rat and rabbits plasma. Stearoyl-L-carnitine chloride acts as a metabolomics biomarker for Parkinson’s disease. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2 .
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- HY-W770914
-
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Stearoyl-L-carnitine chloride- 13C3 is the 13C-labeled Stearoyl-L-carnitine chloride (HY-130466). Stearoyl-L-carnitine chloride is an endogenous long-chain acylcarnitine. Stearoyl-L-carnitine chloride is a less potent inhibitor of GlyT2. Stearoyl-L-carnitine chloride inhibits glycine responses by 16.8% at concentrations up 3 μM .
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- HY-113147S1
-
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L-Palmitoylcarnitine-d9 is deuterium labeled L-Palmitoylcarnitine. L-Palmitoylcarnitine, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .
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- HY-152013S
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L-Palmitoylcarnitine-d3-1 (hydrochloride) is deuterium labeled L-Palmitoylcarnitine (chloride). L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2 .
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- HY-W014787S
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Decanedioic acid-d4 is the deuterium labeled Decanedioic acid (HY-W014787). Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency .
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- HY-W014787S1
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Decanedioic acid-d16 is the deuterium labeled Decanedioic acid (HY-W014787). Decanedioic acid is a straight-chain dicarboxylic acid. Dodecanedioic acid overcomes metabolic inflexibility in type 2 diabetes. Decanedioic acid prevents and reverses metabolic-associated liver disease and obesity. Decanedioic acid is associated with carnitine-acylcarnitine translocase deficiency and medium chain acyl-CoA dehydrogenase deficiency .
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