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Results for "

11:0 PC

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Androgen Receptor (1) Biochemical Assay Reagents (2) MMP (1) Raf (1)
By Research Areas:	Cancer (2) Inflammation/Immunology (1)

Inhibitors & Agonists

Screening Libraries

Biochemical Assay Reagents

Targets Recommended: Pyruvate Carboxylase (PC)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W339358

11:0 PC 1,2-Diundecanoyl-sn-glycero-3-phosphocholine	Biochemical Assay Reagents	Others
11:0 PC (1,2-Diundecanoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine, which plays a role in the folding of intact, functionally competent integral membrane proteins .

HY-166989

1-undecanoyl-2-hydroxy-sn-glycero-3-phosphocholine 11:0 Lyso PC	Biochemical Assay Reagents	Others
1-Undecanoyl-sn-glycero-3-phosphocholine is a biochemical assay reagent.

HY-147852

B-Raf IN 7	Raf	Cancer
B-Raf IN 7 (compound 6a) is a potent B-Raf inhibitor, with an IC₅₀ of 110.23 nM. B-Raf IN 7 exhibits antitumor activity against colon carcinoma (HCT-116), mammary gland (MCF-7), hepatocellular carcinoma (HEPG-2), human cervical carcinoma (Hela) and human prostate cancer (PC-3) cells, with IC₅₀ values of 7.50, 9.87, 10.57, 11.63 and 12.83 µM .

HY-NP110

Highly purified Type II collagen, from mouse sternal cartilage Mouse Type II collagen, immunization grade	MMP	Inflammation/Immunology
Highly purified Type II collagen, from mouse sternal cartilage (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

HY-403733C

JJ-450	Androgen Receptor	Cancer
JJ-450 is a non-competitive antagonist androgen receptor (AR) that inhibits the transcriptional activity of wild-type AR and mutant AR ^F876L. JJ-450 has an IC₅₀ of approximately 1-10 μM in inhibiting AR transcriptional activity in PC3 cells. It is selective for AR binding and does not compete with androgens for binding to the ligand binding domain (LBD) of AR. JJ-450 inhibits the transcriptional activity of AR and its splice variants (such as AR ^F876L) by inhibiting AR nuclear translocation and promoting the degradation of unliganded AR in the nucleus. JJ-450 can be used in castration-resistant prostate cancer (CRPC) studies that are resistant to Enzalutamide (MDV3100) (HY-70003) .

Cat. No.	Product Name

HY-L110

Cyclic Peptide Library	92 compounds
Cyclic peptides are polypeptide chains taking cyclic ring structure, which exhibit diverse biological activities, such as antibacterial activity, immunosuppressive activity and anti-tumor activity. Cyclic peptides, with the features of good binding affinity, target selectivity and low toxicity, show great success as therapeutics. Multiple cyclic peptides are currently in clinical use, for examples, gramicidin and tyrocidine with bactericidal activity, cyclosporin A with immunosuppressive activity, and vancomycin with antibacterial activity. Furthermore, cyclic peptides usually have the sufficient size and a balanced conformational flexibility/rigidity for binding to flat protein-protein interaction (PPI) interfaces, which have potential to develop PPI drugs. MCE offers a unique collection of 92 cyclic peptides, all of which have good bioactivities. MCE Cyclic Peptide Library is a powerful tool for drug discovery and PPI inhibitor screening.

Cyclic Peptide Library

92 compounds

Cyclic peptides are polypeptide chains taking cyclic ring structure, which exhibit diverse biological activities, such as antibacterial activity, immunosuppressive activity and anti-tumor activity. Cyclic peptides, with the features of good binding affinity, target selectivity and low toxicity, show great success as therapeutics. Multiple cyclic peptides are currently in clinical use, for examples, gramicidin and tyrocidine with bactericidal activity, cyclosporin A with immunosuppressive activity, and vancomycin with antibacterial activity. Furthermore, cyclic peptides usually have the sufficient size and a balanced conformational flexibility/rigidity for binding to flat protein-protein interaction (PPI) interfaces, which have potential to develop PPI drugs.

MCE offers a unique collection of 92 cyclic peptides, all of which have good bioactivities. MCE Cyclic Peptide Library is a powerful tool for drug discovery and PPI inhibitor screening.

Cat. No.	Product Name	Type

HY-W339358

11:0 PC 1,2-Diundecanoyl-sn-glycero-3-phosphocholine	Drug Delivery
11:0 PC (1,2-Diundecanoyl-sn-glycero-3-phosphocholine) is a phosphatidylcholine, which plays a role in the folding of intact, functionally competent integral membrane proteins .

HY-166989

1-undecanoyl-2-hydroxy-sn-glycero-3-phosphocholine 11:0 Lyso PC	Drug Delivery
1-Undecanoyl-sn-glycero-3-phosphocholine is a biochemical assay reagent.

HY-NP110

Highly purified Type II collagen, from mouse sternal cartilage Mouse Type II collagen, immunization grade	Native Proteins
Highly purified Type II collagen, from mouse sternal cartilage (Mouse Type II collagen, immunization grade) is an immune grade collagen derived from mouse sternal cartilage, which can stimulate the animal's immune system to produce specific antibodies against this collagen. Collagen is also a substrate for hydrolysis by MMPs .

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