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Sae1

" in MedChemExpress (MCE) Product Catalog:
Recombinant Proteins Recommended:
Cat. No. Compare Product Name Species Source
  • HY-P71643
    SAE1 Protein, Human (GST)

    Activator of SUMO1; AOS1; HSPC140; Sae1; Sae1_HUMAN; Sentrin/SUMO activating protein AOS1; UBL E1A; UBLE1A

    		 Human E. coli
    SAE1 protein, forming a heterodimer, acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and potentially SUMO4. It critically mediates ATP-dependent activation of SUMO proteins, enabling the formation of a thioester bond with UBA2/SAE2's active site cysteine. This process is essential for protein modification through sumoylation. SAE1 Protein, Human (GST) is the recombinant human-derived SAE1 protein, expressed by E. coli , with N-GST labeled tag.

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