2. Recombinant Proteins
  3. Biotinylated Proteins
  4. Vitronectin Protein, Human (Biotinylated)

Vitronectin is a multifunctional cell adhesion factor in serum and tissues that interacts with glycosaminoglycans and proteoglycans. It acts as an adhesion molecule between cells and the matrix, binding to specific integrins. Vitronectin Protein, Human (Biotinylated) is the recombinant human-derived Vitronectin protein, expressed by HEK293 , with tag free. The total length of Vitronectin Protein, Human (Biotinylated) is 379 a.a., with molecular weight of 47-55 kDa.

For research use only. We do not sell to patients.

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Description

Vitronectin is a multifunctional cell adhesion factor in serum and tissues that interacts with glycosaminoglycans and proteoglycans. It acts as an adhesion molecule between cells and the matrix, binding to specific integrins. Vitronectin Protein, Human (Biotinylated) is the recombinant human-derived Vitronectin protein, expressed by HEK293 , with tag free. The total length of Vitronectin Protein, Human (Biotinylated) is 379 a.a., with molecular weight of 47-55 kDa.
Background

Vitronectin Protein is a multifunctional cell adhesion and spreading factor present in serum and tissues. It interacts with glycosaminoglycans and proteoglycans and acts as a cell-to-substrate adhesion molecule, binding to specific integrins. Additionally, Vitronectin Protein functions as an inhibitor of the terminal cytolytic complement pathway, protecting cell membranes from damage. It also possesses protease-inhibiting activity and is involved in regulating growth hormone-dependent processes, specifically somatomedin-B.
Species

Human
Source

HEK293
Tag

Tag Free
Accession

P04004 (D20-R398)
Gene ID
Molecular Construction
N-term
Vitronectin (D20-R398)
Accession # P04004
C-term
Synonyms
VTN; V75; VN; Vitronectin; S-protein; Serum-spreading factor
Molecular Weight

47-55 kDa
Purity

Greater than 90% as determined by reducing SDS-PAGE.
Endotoxin Level

<1 EU/μg, determined by LAL method.
Documentation
Handling Instructions (2659 KB)

Vitronectin Protein, Human (Biotinylated) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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Vitronectin Protein, Human (Biotinylated)
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