STEAP1 Protein, Human (HEK293, His)

STEAP1 protein lacks the necessary binding sites for the electron-donating substrate NADPH, therefore it does not function as a metalloreductase. However, when fused to the NADPH-binding domain of STEAP4, it can facilitate the reduction of Fe(3+). STEAP1 Protein, Human (HEK293, His) is the recombinant human-derived STEAP1 protein, expressed by HEK293 , with C-His labeled tag. The total length of STEAP1 Protein, Human (HEK293, His) is 338 a.a., with molecular weight of ~31 kDa.

STEAP1 Protein, a member of the six-transmembrane epithelial antigen of the prostate family, is involved in iron regulation and tumor progression. It is overexpressed in various cancers and contributes to cell proliferation and metastasis. The potential of STEAP1 Protein as a therapeutic target and its role in cancer development make it a subject of interest in oncology research.

Human

HEK293

C-His

Q9UHE8 (Q2-L339)

26872  [NCBI]

Approximately 31 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.