BTN3A1/CD277 Protein, Cynomolgus (HEK293, His)

BTN3A1/CD277 protein belongs to the immunoglobulin superfamily and part of the BTN/MOG family and plays a key role in immune regulation. It is mainly expressed on antigen-presenting cells and interacts with immune cells, especially γδ T cells, affecting their activation, proliferation and cytokine production. BTN3A1/CD277 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived BTN3A1/CD277 protein, expressed by HEK293 , with C-His labeled tag. The total length of BTN3A1/CD277 Protein, Cynomolgus (HEK293, His) is 218 a.a., with molecular weight of ~30 kDa.

BTN3A1/CD277 Protein belongs to the immunoglobulin superfamily and specifically the BTN/MOG family. This protein plays a crucial role in immune regulation and has been implicated in various immune-related processes. BTN3A1/CD277 is predominantly expressed on the surface of antigen-presenting cells, such as dendritic cells and monocytes, where it interacts with other immune cells to modulate their function. It is involved in the activation of γδ T cells, a subset of T cells that possess unique characteristics and contribute to both innate and adaptive immune responses. BTN3A1/CD277 is known to regulate the activation and proliferation of γδ T cells, as well as their cytokine production. Additionally, this protein is also associated with the regulation of natural killer (NK) cell function. By understanding the precise mechanisms and signaling pathways involving BTN3A1/CD277, researchers aim to develop therapeutic strategies for immune-related disorders and harness its potential for immunotherapy.

Cynomolgus

HEK293

C-His

A0A330KVC6 (Q1-S218)

/

Approximately 30 kDa

Greater than 95% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.