2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. R1663

R1663 is a factor Xa inhibitor with anticoagulant activity. R1663 does not affect bleeding time. The pharmacodynamic effects (such as inhibition of thrombin generation) and plasma concentrations of R1663 are dose-dependent. R1663 prolongs clotting time in a concentration-dependent manner and inhibits the peak height of thrombin generation and endogenous thrombin potential.

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R1663

R1663 Chemical Structure

CAS No. : 865451-66-7

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Description

R1663 is a factor Xa inhibitor with anticoagulant activity. R1663 does not affect bleeding time. The pharmacodynamic effects (such as inhibition of thrombin generation) and plasma concentrations of R1663 are dose-dependent. R1663 prolongs clotting time in a concentration-dependent manner and inhibits the peak height of thrombin generation and endogenous thrombin potential[1].

Molecular Weight

519.90

Formula

C24H21ClF3N5O3
CAS No.
SMILES

O=C([C@H]1CN(CC(F)F)C[C@@H]1C(NC2=CC=C(N3C=CC=CC3=O)C=C2F)=O)NC4=NC=C(Cl)C=C4
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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R1663 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

R1663865451-66-7R 1663R-1663Endogenous MetaboliteInhibitorinhibitorinhibit

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