2. Academic Validation
  3. Mutalomycin, a new polyether antibiotic taxonomy, fermentation, isolation and characterization

Mutalomycin, a new polyether antibiotic taxonomy, fermentation, isolation and characterization

  • J Antibiot (Tokyo). 1977 Nov;30(11):903-7. doi: 10.7164/antibiotics.30.903.
T Fehr,  H D King,  M Kuhn
PMID: 591458 DOI: 10.7164/antibiotics.30.903
Abstract

Mutalomycin is a new metal-complexing polyether Antibiotic produced by a strain of Streptomyces mutabilis NRRL 8088. The metabolite, a monocarboxylic acid, was isolated as the sodium salt C41H69NaO12. The structure of this polyether was established by X-ray analysis of its potassium salt C41H69KO12. Mutalomycin contains six heterocyclic rings and is structurally related to nigericin. The metabolite is active against gram-positive bacteria and Eimeria tenella (chicken coccidiosis).

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