2. Academic Validation
  3. Endophenazines A-D, new phenazine antibiotics from the athropod associated endosymbiont Streptomyces anulatus II. Structure elucidation

Endophenazines A-D, new phenazine antibiotics from the athropod associated endosymbiont Streptomyces anulatus II. Structure elucidation

  • J Antibiot (Tokyo). 2002 Sep;55(9):801-6. doi: 10.7164/antibiotics.55.801.
Philipp Krastel 1,  Axel Zeeck,  Klaus Gebhardt,  Hans-Peter Fiedler,  Joachim Rheinheimer
Affiliations

Affiliation

  • 1 Institut für Organische Chemie, Universität Göttingen, Tammannstrasse 2, D-37077 Göttingen, Germany.
PMID: 12458769 DOI: 10.7164/antibiotics.55.801
Abstract

A detailed screening of the secondary metabolite pattern produced by different athropod associated strains of the species Streptomyces anulatus resulted in the isolation and structure elucidation of the endophenazines A-D (2, 4-6). The structures were assigned by spectroscopic methods and chemical transformations. 4 represents a chromophoric system based on a phenazin-7-one, 5 and 6 are new 5,10-dihydrophenazine derivatives.

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