1. Academic Validation
  2. Quinolactacins A, B and C: novel quinolone compounds from Penicillium sp. EPF-6. II. Physico-chemical properties and structure elucidation

Quinolactacins A, B and C: novel quinolone compounds from Penicillium sp. EPF-6. II. Physico-chemical properties and structure elucidation

  • J Antibiot (Tokyo). 2000 Nov;53(11):1252-6. doi: 10.7164/antibiotics.53.1252.
S Takahashi 1 N Kakinuma H Iwai T Yanagisawa K Nagai K Suzuki T Tokunaga A Nakagawa
Affiliations

Affiliation

  • 1 Department of Biosciences, Teikyo University, Utsunomiya, Japan.
Abstract

Three novel Quinolone compounds, quinolactacins A (1), B (2) and C (3), have been found from the fermentation broth of Penicillium sp. EPF-6, a fungus isolated from the larvae of mulberry pyralid (Margaronia pyloalis Welker). The molecular formulas of 1, 2 and 3 were determined to be C16H18N2O2, C15H16N2O2 and C16H18N2O3, respectively by FAB-MS and NMR spectral analyses. The structures of these compounds have a novel Quinolone skeleton with a gamma-lactam ring consisting of C12H8N2O2 as the common chromophore.

Figures
Products