Lipohexin

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Lipohexin is a peptide antibiotic. Lipohexin has anti-Gram-positive bacterial effect. Lipohexin had competitive inhibitory effect on human placental proline endopeptidase with an IC₅₀ of 3.5 μM. Lipohexin inhibits the proline endopeptidase from the Flavobacterium meningoseptiu with an IC₅₀ of 25 μM.

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Lipohexin Chemical Structure

CAS No. : 193751-58-5

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Description	Lipohexin is a peptide antibiotic. Lipohexin has anti-Gram-positive bacterial effect. Lipohexin had competitive inhibitory effect on human placental proline endopeptidase with an IC₅₀ of 3.5 μM. Lipohexin inhibits the proline endopeptidase from the Flavobacterium meningoseptiu with an IC₅₀ of 25 μM^[1].
Molecular Weight	764.99
Formula	C₃₉H₆₈N₆O₉
CAS No.	193751-58-5
SMILES	OC(CCNC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC(C(C)(C)NC([C@H]1N(CCC1)C(C(C)C(CCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O
Structure Classification	Others
Initial Source	Microorganisms Moeszia lindtneri
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. S Heinze, et al. Lipohexin, a new inhibitor of prolyl endopeptidase from Moeszia lindtneri (HKI-0054) and Paecilomyces sp. (HKI-0055; HKI-0096). I. Screening, isolation and structure elucidation. J Antibiot (Tokyo). 1997 May;50(5):379-83. [Content Brief]

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lipohexin193751-58-5Prolyl Endopeptidase (PREP)BacterialAntibioticprolyl oligopeptidasePOPInhibitorinhibitorinhibit

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Lipohexin

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