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  3. Leupeptin Ac-LL hydrochloride

Leupeptin Ac-LL (hydrochloride) is the hydrochloride form of Leupeptin Ac-LL (HY-18234B). Leupeptin Ac-LL (hydrochloride) has better inhibition than Leupeptin Ac-LL.

For research use only. We do not sell to patients.

Leupeptin Ac-LL hydrochloride

Leupeptin Ac-LL hydrochloride Chemical Structure

CAS No. : 24125-16-4

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Based on 1 publication(s) in Google Scholar

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Description

Leupeptin Ac-LL (hydrochloride) is the hydrochloride form of Leupeptin Ac-LL (HY-18234B). Leupeptin Ac-LL (hydrochloride) has better inhibition than Leupeptin Ac-LL[1].

Molecular Weight

463.01

Formula

C20H39ClN6O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC(C)C[C@H](NC(C)=O)C(N[C@@H](CC(C)C)C(NC(C=O)CCCNC(N)=N)=O)=O.Cl

Structure Classification
Initial Source

Actinomycetes

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (269.97 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1598 mL 10.7989 mL 21.5978 mL
5 mM 0.4320 mL 2.1598 mL 4.3196 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

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Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 2.1598 mL 10.7989 mL 21.5978 mL 53.9945 mL
5 mM 0.4320 mL 2.1598 mL 4.3196 mL 10.7989 mL
10 mM 0.2160 mL 1.0799 mL 2.1598 mL 5.3995 mL
15 mM 0.1440 mL 0.7199 mL 1.4399 mL 3.5996 mL
20 mM 0.1080 mL 0.5399 mL 1.0799 mL 2.6997 mL
25 mM 0.0864 mL 0.4320 mL 0.8639 mL 2.1598 mL
30 mM 0.0720 mL 0.3600 mL 0.7199 mL 1.7998 mL
40 mM 0.0540 mL 0.2700 mL 0.5399 mL 1.3499 mL
50 mM 0.0432 mL 0.2160 mL 0.4320 mL 1.0799 mL
60 mM 0.0360 mL 0.1800 mL 0.3600 mL 0.8999 mL
80 mM 0.0270 mL 0.1350 mL 0.2700 mL 0.6749 mL
100 mM 0.0216 mL 0.1080 mL 0.2160 mL 0.5399 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Leupeptin Ac-LL hydrochloride
Cat. No.:
HY-18234C
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