2. Gene
  3. Nans - N-acetylneuraminic acid synthase (sialic acid synthase) Gene

Nans - N-acetylneuraminic acid synthase (sialic acid synthase) Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Sas; 4632418E04Rik

Gene ID: 94181 | Gene type: protein coding

About Nans

Summary

Enables N-acylneuraminate-9-phosphate synthase activity. Predicted to be involved in glycosylation. Located in cytosol. Is expressed in several structures, including alimentary system; sensory organ; skeleton; skin; and tarsus. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Genevieve-type. Orthologous to human NANS (N-acetylneuraminate synthase). [provided by Alliance of Genome Resources, Apr 2022]

Nans Products(1)

mRNA Protein Name
NM_053179.3 NP_444409.1 sialic acid synthase
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables N-acylneuraminate-9-phosphate synthase activity IDA
IDA: Inferred from direct assay
10873658 MGI
Cellular Component GO Annotation Evidence Reference Source
is active in cytosol IDA
IDA: Inferred from direct assay
10873658 MGI
located in cytosol IDA
IDA: Inferred from direct assay
10873658 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sialic acid synthase

N-acetylneuraminate-9-phosphate synthase

N-acetylneuraminic acid 9-phosphate synthetase

N-acetylneuraminic acid phosphate synthase

Related Agents

Pre-clinical Phase
Bioactive Molecules (6)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-19818A NAN-190 hydrobromide Antagonist 99.11% Unkown
HY-19818 NAN-190 / Unkown
HY-RS09025 NANS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-124449 Afidopyropen Modulator / Unkown
HY-RS20302 Nans Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26810 Nans Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Nans NCBI NCBI:54187