2. Gene
  3. Tie1 - tyrosine kinase with immunoglobulin-like and EGF-like domains 1 Gene

Tie1 - tyrosine kinase with immunoglobulin-like and EGF-like domains 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 89806 | Gene type: protein coding

About Tie1

Summary

Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in vasculogenesis. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human TIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1). [provided by Alliance of Genome Resources, Apr 2022]

Tie1 Products(1)

mRNA Protein Name
NM_053545.1 NP_445997.1 tyrosine-protein kinase receptor Tie-1 precursor
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in vasculogenesis IDA
IDA: Inferred from direct assay
10474040 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

tyrosine-protein kinase receptor Tie-1

tyrosine kinase receptor 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (7)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14514 TIAL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14520 TIE1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-15973 BSF-466895 Inhibitor / Unkown
HY-RS19390 Tie1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22860 Tial1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25882 Tie1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29374 Tial1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Inhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-P991384 DX-2240 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Tie1 NCBI NCBI:7075