2. Gene
  3. LSS - Lss lanosterol synthase Gene

LSS - Lss lanosterol synthase Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81681 | Gene type: protein coding

About LSS

Summary

Enables lanosterol synthase activity. Involved in Cholesterol biosynthetic process. Located in intracellular membrane-bounded organelle. Human ortholog(s) of this gene implicated in alopecia-mental retardation syndrome 4; cataract; cataract 44; and hypotrichosis 14. Orthologous to human LSS (lanosterol synthase). [provided by Alliance of Genome Resources, Apr 2022]

LSS Products(1)

mRNA Protein Name
NM_031049.2 NP_112311.2 lanosterol synthase
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables lanosterol synthase activity IDA
IDA: Inferred from direct assay
1429550 RGD
enables lanosterol synthase activity IMP
IMP: Inferred from mutant phenotype
7568116 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cholesterol biosynthetic process IDA
IDA: Inferred from direct assay
1429550 RGD
involved in cholesterol biosynthetic process IMP
IMP: Inferred from mutant phenotype
16440058 RGD
involved in sterol metabolic process IMP
IMP: Inferred from mutant phenotype
16440058 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lanosterol synthase

2,3-epoxysqualene--lanosterol cyclase

2,3-oxidosqualene: lanosterol cyclase

OSC

lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)

oxidosqualene--lanosterol cyclase

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-160972 MM0299 Inhibitor 98.51% Unkown
HY-RS07706 LMBR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07866 LSS Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17396 Lss Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23851 Lss Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens LSS NCBI NCBI:4047