2. Gene
  3. PFN2 - Pfn2 profilin 2 Gene

PFN2 - Pfn2 profilin 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 81531 | Gene type: protein coding

About PFN2

Summary

Enables actin binding activity. Involved in regulation of actin filament polymerization. Predicted to be located in postsynapse and terminal bouton. Predicted to be active in several cellular components, including Schaffer collateral - CA1 synapse; glutamatergic synapse; and presynapse. Orthologous to human PFN2 (profilin 2). [provided by Alliance of Genome Resources, Apr 2022]

PFN2 Products(1)

mRNA Protein Name
NM_030873.2 NP_110500.2 profilin-2
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables actin binding IDA
IDA: Inferred from direct assay
11027290 RGD
Biological Process GO Annotation Evidence Reference Source
involved in regulation of actin filament polymerization IDA
IDA: Inferred from direct assay
11027290 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

profilin-2

profilin II

profilin-2-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10369 PFN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19627 Pfn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20991 Mpeg1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26123 Pfn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens PFN2 NCBI NCBI:5217