1. Gene
  2. Hspb8 - heat shock protein 8 Gene

Hspb8 - heat shock protein 8 Gene

Mus musculus

Also known as H11; H11K; Cryac; E2IG1; HSP22; D5Ucla4; HSP20-like

Gene ID: 80888 | Gene type: protein coding

About Hspb8

Summary

Predicted to enable protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to be located in cytosol and nuclear body. Predicted to be part of chaperone complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study distal hereditary motor neuronopathy type 2A. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and distal hereditary motor neuronopathy type 2A. Orthologous to human HSPB8 (heat shock protein family B (small) member 8). [provided by Alliance of Genome Resources, Apr 2022]

Hspb8 Products(1)

mRNA Protein Name
NM_030704.3 NP_109629.1 heat shock protein beta-8
Gene Ontology
  • Molecular Function
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20060297 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

heat shock protein beta-8

alpha-crystallin C chain

crystallin, alpha C

heat shock 27kDa protein 8

heat shock protein 20-like protein

small stress protein-like protein HSP22

Orthologs Information

Species Symbol Source ID
Homo sapiens Hspb8 NCBI NCBI:26353