2. Gene
  3. Epha5 - EPH receptor A5 Gene

Epha5 - EPH receptor A5 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Els1; EHK-1; Els1.

Gene ID: 79208 | Gene type: protein coding

About Epha5

Summary

Enables Ephrin Receptor activity and growth factor binding activity. Involved in several processes, including cAMP-mediated signaling; dendritic spine morphogenesis; and Ephrin Receptor signaling pathway. Acts upstream of or within negative regulation of cell adhesion. Located in axon and plasma membrane. Orthologous to human EphA5 (EPH receptor A5). [provided by Alliance of Genome Resources, Apr 2022]

Epha5 Products(2)

mRNA Protein Name
NM_001169137.3 NP_001162608.1 ephrin type-A receptor 5 isoform 1 precursor
NM_024367.2 NP_077343.1 ephrin type-A receptor 5 isoform 2
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables ephrin receptor activity IDA
IDA: Inferred from direct assay
20824214 RGD
enables growth factor binding IPI
IPI: Inferred from physical interaction
22568954 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
20824214 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cAMP-mediated signaling IDA
IDA: Inferred from direct assay
20824214 RGD
involved in dendritic spine morphogenesis IDA
IDA: Inferred from direct assay
20824214 RGD
involved in ephrin receptor signaling pathway IDA
IDA: Inferred from direct assay
20824214 RGD
acts upstream of or within negative regulation of cell adhesion IDA
IDA: Inferred from direct assay
23242526 RGD
involved in positive regulation of CREB transcription factor activity IMP
IMP: Inferred from mutant phenotype
20824214 RGD
Cellular Component GO Annotation Evidence Reference Source
located in axon IDA
IDA: Inferred from direct assay
7748564 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
7748564 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ephrin type-A receptor 5

EPH homology kinase 1

eck-like sequence 1

tyrosine-protein kinase receptor EHK-1

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04429 EPHA5 Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-146375 UniPR505 Antagonist / Unkown
HY-RS18661 Epha5 Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS25147 Epha5 Rat Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Epha5 NCBI NCBI:2044
Macaca fascicularis Epha5 NCBI NCBI:102138762
Mus musculus Epha5 NCBI NCBI:13839