ZNF236 - zinc finger protein 236 Gene

Homo sapiens

Also known as ZNF236A; ZNF236B

Gene ID: 7776 | Gene type: protein coding

About ZNF236

Cytogenetic location: 18q23 Genomic coordinates (GRCh38): 18:76,822,557-76,972,901 (from NCBI)

This gene has 9 transcripts (splice variants) and 214 orthologues. Broad expression in testis (RPKM 5.8), ovary (RPKM 2.3) and 24 other tissues.

Summary

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in cellular response to glucose stimulus. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ZNF236 Products(2)

mRNA	Protein	Name
NM_001306089.2	NP_001293018.1	zinc finger protein 236 isoform 1
NM_007345.4	NP_031371.3	zinc finger protein 236 isoform 2

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables protein binding	IPI IPI: Inferred from physical interaction	32296183	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in cellular response to glucose stimulus	IEP IEP: Inferred from expression pattern	9299475	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ZNF236 Protein Structure

zf-H2C2_2

zf-C2H2

zf-H2C2_2

zf-C2H2_4

zf-H2C2_2

zf-C2H2

zf-H2C2_2

0
300
600
900
1200
1500
1845 a.a.

Protein Preferred Names

Protein Names

zinc finger protein 236

regulated by glucose

Related Diseases

Diseases

Alias

Chromosome 18q Deletion Syndrome

18q- Syndrome	Monosomy 18q
Deletion Of Long Arm Of Chromosome 18	Chromosome 18q- Syndrome
Deletion 18q	18q Deletion Syndrome
Distal 18q Deletion Syndrome	Chromosome 18 Long Arm Deletion Syndrome
Chromosome 18q Monosomy	Del Syndrome
Chromosome 18 Deletion Syndrome

Hypothyroidism, Thyroidal Or Athyroidal, With Spiky Hair And Cleft Palate

Bamforth-Lazarus Syndrome	Bamforth Syndrome
Hypothyroidism, Athyroidal, With Spiky Hair And Cleft Palate	Hypothyroidism Cleft Palate Hypothyroidism, Athyroidal, With Spiky Hair And Cleft Palate
Athyroidal Hypothyroidism-Spiky Hair-Cleft Palate Syndrome	Hypothyroidism-Cleft Palate Syndrome
BLS	Athyroidal Hypothyroidism With Spiky Hair And Cleft Palate

Childhood Disintegrative Disease

Childhood Disintegrative Disorder	Disintegrative Psychosis
Heller'S Syndrome	Symbiotic Psychosis
Dementia Infantilis	Heller Syndrome
Shared Paranoid Disorder

Cleft Palate, Isolated

Cleft Palate	Isolated Cleft Palate
CPI	Cp
Palatoschisis	Cleft Palate Isolated
Uranostaphyloschisis	Congenital Fissure Of Palate
Cleft Of Secondary Palate

Van Der Woude Syndrome

Lip-Pit Syndrome	Vws
Cleft Lip And/Or Palate With Mucous Cysts Of Lower Lip	Vdws
Lps	Lip Pit Syndrome
Cleft Lip/Palate With Mucous Cysts Of Lower Lip	Myopathy, Actin, Congenital, With Excess Of Thin Myofilaments

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS16113	ZNF236 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	ZNF236	MGD	MGI:1926950
Bos taurus	ZNF236	VGNC	VGNC:37231
Macaca mulatta	ZNF236	VGNC	VGNC:78879
Canis familiaris	ZNF236	VGNC	VGNC:48678
Rattus norvegicus	ZNF236	RGD	RGD:1309670
Felis catus	ZNF236	VGNC	VGNC:67280

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