RGPD2 - RANBP2 like and GRIP domain containing 2 Gene

Homo sapiens

Also known as RGP2; NUP358; RANBP2L2

Gene ID: 729857 | Gene type: protein coding

About RGPD2

Cytogenetic location: 2p11.2 Genomic coordinates (GRCh38): 2:87,755,960-87,989,818 (from NCBI)

This gene has 2 transcripts (splice variants), 21 orthologues and 10 paralogues. Broad expression in testis (RPKM 17.3), placenta (RPKM 6.4) and 23 other tissues.

Summary

Predicted to contribute to GTPase activator activity. Predicted to be involved in NLS-bearing protein import into nucleus. Predicted to be part of nuclear pore. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RGPD2 Products(2)

mRNA	Protein	Name
NM_001078170.3	NP_001071638.2	RANBP2-like and GRIP domain-containing protein 2 isoform 1
NM_001393613.1	NP_001380542.1	RANBP2-like and GRIP domain-containing protein 2 isoform 2

RGPD2 Protein Structure

TPR_1

Ran_BP1

GRIP

0
300
600
900
1200
1500
1756 a.a.

Protein Preferred Names

Protein Names

RANBP2-like and GRIP domain-containing protein 2

Ran binding protein 2-like 2

Related Diseases

Diseases

Alias

Charcot-Marie-Tooth Disease, Axonal, Type 2dd

CMT2DD	Charcot-Marie-Tooth Neuropathy, Type 2dd
Charcot-Marie-Tooth Disease Type 2dd	Atp1a1-Related Autosomal Dominant Charcot-Marie-Tooth Disease Type 2
Atp1a1-Related Cmt2	Autosomal Dominant Charcot-Marie-Tooth Disease Type 2dd
Charcot-Marie-Tooth Disease 2dd

Achalasia-Addisonianism-Alacrima Syndrome

Allgrove Syndrome	Triple-A Syndrome
Achalasia-Addisonianism-Alacrimia Syndrome	Alacrima-Achalasia-Adrenal Insufficiency Neurologic Disorder
Triple A Syndrome	Aaa Syndrome
AAAS	Glucocorticoid Deficiency With Achalasia
Glucocorticoid Deficiency And Achalasia	Addisonian-Achalasia Syndrome
Hypoadrenalism With Achalasia	Alacrima-Achalasia-Addisonianism
Aaa	Acth-Resistant Adrenal Insufficiency, Achalasia And Alacrima
Achalasia Addisonianism Alacrimia Syndrome	Achalasia Alacrima Syndrome
Addisonian Achalasia Syndrome	Achalasia-Addisonian Syndrome
Achalasia-Alacrima Syndrome	2a Syndrome
3a Syndrome	4a Syndrome
Adrenal Insufficiency-Achalasia-Alacrima Syndrome	Double A Syndrome
Quaternary A Syndrome	Acth-Resistant Adrenal Insufficiency With Achalasia And Alacrima
Allgrove'S Syndrome	Adrenal Gland Hypofunction
Adrenal Cortical Hypofunction

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS11898	RGPD1 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS11899	RGPD2 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	RGPD2	MGD	MGI:894323

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