2. Gene
  3. Unc13d - unc-13 homolog D Gene

Unc13d - unc-13 homolog D Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Jinx; Munc13-4; mFLJ00067; 2610108D09Rik

Gene ID: 70450 | Gene type: protein coding

About Unc13d

Summary

Predicted to enable small GTPase binding activity. Involved in platelet dense granule organization; positive regulation of substrate adhesion-dependent cell spreading; and vasculature development. Acts upstream of or within several processes, including defense response to Other organism; germinal center formation; and granuloma formation. Predicted to be located in cytosol; lysosome; and secretory vesicle. Used to study familial hemophagocytic lymphohistiocytosis 3. Human ortholog(s) of this gene implicated in familial hemophagocytic lymphohistiocytosis 3. Orthologous to human UNC13D (unc-13 homolog D). [provided by Alliance of Genome Resources, Apr 2022]

Unc13d Products(1)

mRNA Protein Name
NM_001009573.2 NP_001009573.2 protein unc-13 homolog D
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
18354201 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within defense response to virus IMP
IMP: Inferred from mutant phenotype
17420270 MGI
acts upstream of or within establishment of localization in cell IMP
IMP: Inferred from mutant phenotype
17420270 MGI
acts upstream of or within germinal center formation IMP
IMP: Inferred from mutant phenotype
17420270 MGI
acts upstream of or within granuloma formation IMP
IMP: Inferred from mutant phenotype
17420270 MGI
acts upstream of or within natural killer cell degranulation IMP
IMP: Inferred from mutant phenotype
17420270 MGI
acts upstream of or within phagocytosis IMP
IMP: Inferred from mutant phenotype
17420270 MGI
involved in positive regulation of substrate adhesion-dependent cell spreading IMP
IMP: Inferred from mutant phenotype
22589474 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein unc-13 homolog D

likely ortholog of H. sapiens unc-13 homolog D (UNC13D)

Related Agents

Pre-clinical Phase
Bioactive Molecules (2)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS15467 UNC13D Human Pre-designed siRNA Set A Pre-designed Sets / Unkown
HY-RS21975 Unc13d Mouse Pre-designed siRNA Set A Pre-designed Sets / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Unc13d NCBI NCBI:201294