2. Gene
  3. Spen - spen family transcriptional repressor Gene

Spen - spen family transcriptional repressor Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as RGD1564662

Gene ID: 690911 | Gene type: protein coding

About Spen

Summary

Predicted to enable several functions, including DNA-binding transcription factor activity; nucleic acid binding activity; and transcription corepressor activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of neurogenesis. Predicted to act upstream of or within negative regulation of transcription, DNA-templated and positive regulation of transcription, DNA-templated. Predicted to be located in nucleoplasm. Predicted to be part of transcription repressor complex. Predicted to be active in nucleus. Orthologous to human SPEN (spen family transcriptional repressor). [provided by Alliance of Genome Resources, Apr 2022]

Spen Products(1)

mRNA Protein Name
NM_001395101.1 NP_001382030.1 msx2-interacting protein
Protein Preferred Names Protein Names

msx2-interacting protein

SPEN homolog, transcriptional regulator

rCG30673-like

Related Agents

Pre-clinical Phase
Bioactive Molecules (5)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-152038 SPEN-IN-1 98.47% Unkown
HY-RS11735 RBM15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13660 SPEN Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20339 Spen Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26847 Spen Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Spen NCBI NCBI:23013