2. Gene
  3. Itga2b - integrin subunit alpha 2b Gene

Itga2b - integrin subunit alpha 2b Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus
Gene ID: 685269 | Gene type: protein coding

About Itga2b

Summary

Enables fibrinogen binding activity. Involved in platelet aggregation and positive regulation of leukocyte migration. Located in cell surface. Human ortholog(s) of this gene implicated in Glanzmann's thrombasthenia; platelet-type bleeding disorder 16; thrombocytopenia; and von Willebrand's disease 1. Orthologous to human ITGA2B (Integrin subunit alpha 2b). [provided by Alliance of Genome Resources, Apr 2022]

Itga2b Products(1)

mRNA Protein Name
XM_001063315.7 XP_001063315.1 integrin alpha-IIb
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables fibrinogen binding IDA
IDA: Inferred from direct assay
11278919 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of leukocyte migration IMP
IMP: Inferred from mutant phenotype
11705748 RGD
Cellular Component GO Annotation Evidence Reference Source
located in cell surface IDA
IDA: Inferred from direct assay
11278919 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

integrin alpha-IIb

integrin alpha 2b (Cd41b)

integrin, alpha 2B

Related Agents

Pre-clinical Phase
Bioactive Molecules (3)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS06949 ITGA2B Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19782 Itga2b Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26279 Itga2b Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Itga2b NCBI NCBI:3674
Mus musculus Itga2b NCBI NCBI:16399